What is Selzentry?Selzentry is a medicine used to treat a specific kind of HIV (human immunodeficiency virus) infection (AIDS) in combination with other anti-HIV medications. Selzentry is a type of HIV medicine called a CCR5 antagonist. It works by lowering the amount of HIV in your blood and increasing the number of certain immune cells to help fight infection.
What is the most important information I should know about Selzentry?You have to take Selzentry with other HIV medications.
Always stay on continuous HIV therapy to control your HIV infection and decrease HIV-related illnesses. Though Selzentry can slow the progress of HIV, it is not a cure. You may continue to develop infections and other complications associated with HIV.
Selzentry does not reduce the risk of passing HIV/AIDS to others through sexual contact, sharing needles, or being exposed to your blood. Always practice safe sex to reduce the risk of transmitting HIV to others. Use latex or polyurethane condoms to lower the chance of sexual contact with any body fluids (such as semen, vaginal secretions, or blood).
Selzentry can cause severe liver impairment or signs of an allergic reaction. Stop taking Selzentry and tell your doctor immediately if you develop a rash, yellowing of your skin or the whites of your eyes, dark urine, vomiting, or right upper stomach pain.
Who should not take Selzentry?Do not take Selzentry if you are allergic to it, any of its ingredients, or if you are taking certain other medications that can interact with Selzentry, and have severe kidney impairment or are on hemodialysis.
What should I tell my doctor before I take the first dose of Selzentry?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Selzentry. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver impairment, have heart problems, have sudden fall in blood pressure, are pregnant, or plan to become pregnant.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults and adolescents ≥16 years: The recommended dose is 150-600 milligrams (mg) twice a day. Your doctor will prescribe the appropriate dose for you based on other medicines you are taking.
If you have severe kidney impairment or have symptoms of sudden fall in blood pressure, your doctor will adjust your dose appropriately.
How should I take Selzentry?Take Selzentry exactly as prescribed by your doctor. You should take Selzentry twice a day and at the same time(s) each day. Swallow Selzentry tablets whole; do not chew them. You can take Selzentry with or without food.
When your Selzentry supply starts to run low, get more from your doctor or pharmacy. It is important that you do not run out of Selzentry. If you stop the medicine for even a short time, the amount of HIV in your body can increase or it can become resistant to the effects of Selzentry.
What should I avoid while taking Selzentry?Do not drive a car or operate heavy machinery if you experience dizziness while you are taking Selzentry.
What are possible food and drug interactions associated with Selzentry?If Selzentry is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Selzentry may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.
What are the possible side effects of Selzentry?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: colds, cough, diarrhea, dizziness, fever, rash, runny nose, sleep disorders, sudden fall in blood pressure, swelling, upper respiratory tract infections, urinary abnormalities
Can I receive Selzentry if I am pregnant or breastfeeding?The effects of Selzentry during pregnancy and breastfeeding are unknown. It is recommended that you do not breastfeed your baby if you are infected with HIV. This is because your baby could become infected with HIV through your breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Selzentry?If you miss a dose of Selzentry, take it as soon as you remember. However, if it is less than 6 hours before your next scheduled dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Selzentry?Store at room temperature