Generic Name: Pegvisomant

  • What is Somavert?

    Somavert is a medicine used to treat acromegaly (a disease caused by the body making too much growth hormone). Somavert is administered subcutaneously (just below the skin).

  • What is the most important information I should know about Somavert?

    Your doctor will perform blood tests before and during your treatment with Somavert to check if your liver is working correctly and to see how you are responding to Somavert. Your dose of Somavert may be changed based on these results.

    When you use Somavert, the doses of antidiabetic medications or certain painkillers may need to be changed.

    Somavert can cause liver problems. Stop Somavert and tell your doctor immediately if you experience yellowing of your skin or the white of your eyes, your urine turns dark, your stools turn light in color, you do not feel like eating for several days, you feel sick to your stomach, you have unexplained tiredness, or you have pain in your stomach area.

  • Who should not take Somavert?

    Do not use Somavert if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Somavert?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Somavert. Also, talk to your doctor about your complete medical history, especially if you have growth hormone tumors, diabetes, liver problems, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 10 milligrams (mg) a day.

    Your doctor will prescribe the appropriate dose for you and will increase or decrease your dose as needed until the desired effect is achieved.

  • How should I take Somavert?

    Your doctor will inject your first dose and will teach you or your caregiver how to mix and inject Somavert.

    Use Somavert exactly as prescribed by your doctor. Do not use extra doses or inject more often without asking your doctor.

    Please review the instructions that came with your prescription on how to properly prepare and inject Somavert.

  • What should I avoid while taking Somavert?

    Do not use any other liquid to mix Somavert other than the liquid that came in the same packaging.

    Do not use Somavert for a condition for which it was not prescribed.

    Do not give Somavert to other people, even if they have the same symptoms you have.

  • What are possible food and drug interactions associated with Somavert?

    If Somavert is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Somavert with any of the following: certain painkillers (such as fentanyl), insulin, or oral antidiabetic medications.

  • What are the possible side effects of Somavert?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abnormal liver function tests, back pain, chest pain, diarrhea, dizziness, "flu-like" symptoms, high blood pressure, infections, injection-site reactions, nausea, pain, swelling, tingling and numbness sensation

  • Can I receive Somavert if I am pregnant or breastfeeding?

    The effects of Somavert during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Somavert?

    If you miss a dose of Somavert, skip the one you missed and return to your regular dosing schedule. Do not inject two doses at once.

  • How should I store Somavert?

    Before mixing, store in the refrigerator. Protect from freezing.

    After mixing, use within 6 hours.