Generic Name: Dasatinib

  • What is Sprycel?

    Sprycel is a medication used to treat certain types of leukemia. Depending on the type of leukemia, it may be used in patients who are newly diagnosed, are no longer benefiting from previous treatments, or who have taken but could not tolerate other treatments.

  • What is the most important information I should know about Sprycel?

    Sprycel may cause low blood cells counts. Your doctor will order blood tests to check your blood cell counts regularly during your treatment. Call your doctor immediately if you have a fever or any signs of an infection while you are taking Sprycel.

    Sprycel may cause severe bleeding. Call your doctor immediately if you notice unusual bleeding, bruising of the skin, bright red or tar-like stools, headache, or loss of consciousness.

    Sprycel can also make your body retain more fluid. Call your doctor if you notice any unusual weight gain, swelling, or shortness of breath.

    Sprycel may cause an abnormal heart rate, heart problems, or a heart attack. Your doctor will monitor the potassium and magnesium levels in your blood and your heart function.

    If you are a sexually active male, you should use a condom during intercourse to prevent pregnancy since Sprycel can cause harm to the unborn baby if pregnancy occurs.

  • Who should not take Sprycel?

    Do not use Sprycel if you are allergic to it or to any of its ingredients.

  • What should I tell my doctor before I take the first dose of Sprycel?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Sprycel. Also, talk to your doctor about your complete medical history, especially if you have a liver, kidney, or heart problem, or if you are lactose intolerant.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 100-140 milligrams (mg) given orally once a day. Your doctor will prescribe the appropriate dose for you.

  • How should I take Sprycel?

    Take Sprycel exactly as prescribed by your doctor. You can take Sprycel with or without meals. Swallow the tablets whole; do not crush, chew, or cut them.

  • What should I avoid while taking Sprycel?

    Do not get pregnant or breastfeed during treatment with Sprycel. Do not drink grapefruit juice while you are on this medication.

  • What are possible food and drug interactions associated with Sprycel?

    If Sprycel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sprycel with the following: alfentanil, atazanavir, carbamazepine, clarithromycin, cyclosporine, dexamethasone, ergotamine, erythromycin, indinavir, itraconazole, ketoconazole, nelfinavir, phenobarbital, phenytoin, pimozide, rifampicin, ritonavir, saquinavir, sirolimus, tacrolimus, or telithromycin.

  • What are the possible side effects of Sprycel?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, fatigue, headache, nausea, skin rash

  • Can I receive Sprycel if I am pregnant or breastfeeding?

    Sprycel should not be used during pregnancy. This medicine may pass into your breast milk and should not be used if you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Sprycel?

    If you miss a dose of Sprycel, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Sprycel?

    Store at room temperature.