Striant

Generic Name: Testosterone

  • What is Striant?

    Striant is a hormone medicine containing testosterone that is used to treat adult men when their bodies do not make any testosterone or not enough testosterone (hypogonadism). Striant is a tablet-like buccal system that is applied to the upper gum area of the mouth.

  • What is the most important information I should know about Striant?

    Striant is a controlled substance that has a potential for abuse and may lead to moderate or low physical dependence or high psychological dependence. Do not give Striant to other people, even if they have the same symptoms as you do.

    Striant should not be used in men with breast cancer or prostate cancer.

    Striant should not be used in women, especially women who are pregnant or breastfeeding.

    Do not take Striant if you are allergic to Striant or any of its ingredients.

    Inspect your gums regularly and talk to your doctor if you see any abnormal gums.

    Tell your doctor if your skin or white part of your eyes turns yellow (jaundice), you have dark urine, pale bowel movements (stool), loss of appetite, nausea, have lower abdominal pain, problems urinating, fluid retention (edema) in your ankles and legs or if you put on weight quickly, penile erections that are painful, occur too frequently, or that last for too long, have enlarged breasts (which sometimes does not go away), or emotional changes such as depression.

    Elderly people may be at higher risk for enlarged prostate and prostate cancer. If you have been told you are at an increased risk of prostate cancer, your doctor should screen and monitor you for prostate cancer before and during treatment with Striant.

    If you have heart, kidney or liver disease, you may experience edema with or without congestive heart failure. You may have to discontinue Striant and take diuretics.

    Tell your doctor if you have breathing problems, including a sleep problem called "sleep apnea," wherein you stop breathing for short times while you are sleeping. This happens more in patients who are overweight or who have lung disease. Tell your doctor if you have breathing problems or if you or your partner notices changes in your breathing when you are sleeping.

    Your doctor may do blood tests to check your red blood cells, liver function, cholesterol levels, testosterone levels and prostate (PSA) while you are using Striant, to see how Striant is affecting your body.

  • Who should not take Striant?

    Do not use Striant if you have breast or prostate cancer, or if you are allergic to Striant. Striant should not be used in women, especially women who are pregnant or breastfeeding.

  • What should I tell my doctor before I take the first dose of Striant?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Striant. Also, talk to your doctor about your complete medical history, especially if you have or had an enlarged prostate or prostate cancer, problems urinating due to an enlarged prostate, kidney or liver problems, swelling, congestive heart failure, hypogonadism (testes produce little or no testosterone), sleep apnea (trouble breathing while sleeping), diabetes, obesity (weight problems), or have heart or lung problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose of Striant is 1 buccal system applied to the gum area twice a day, in the morning and evening, about 12 hours apart. Each delivery system contains 30 milligrams (mg) of testosterone.

  • How should I take Striant?

    Use Striant twice a day, once in the morning and once in the evening.

    Once you remove the paper backing, push the buccal system through foil from the front. Striant is flat on one side (the side with the company logo) and curved on the other. This is the side that will face your gum.

    Before you apply Striant, locate the area on your upper gum just above either the left or right incisor (the tooth just to the right or left of your two front teeth). Place Striant in a comfortable spot just above the incisor tooth (on either side of the mouth). Placing the flat side of the Striant system on your fingertip, gently push the curved side against your upper gum. Push the Striant system up as high as it will go on the gum. If you have applied Striant correctly, the flat side will be facing your cheek.

    Using your finger on the outside of your upper lip, hold the Striant buccal system in place for 30 seconds to adhere it securely to your gum or cheek. As the Striant buccal system absorbs moisture from your mouth, it will begin to soften and mold to the shape of your gum. You should be aware that Striant does not dissolve completely, but will remain in place for 12 hours.

    Striant is made to stay in place until you remove it. Remove Striant by gently sliding it to the front or back of your mouth to loosen it. Then slide it downwards from your gum to your tooth. This will avoid scratching the gum.

    With each application, you should rotate Striant to alternate sides of your mouth.

    If Striant does not stick or falls off within the first 8 hours, remove the original system and apply a new one. This counts as replacing the first dose. Apply the next system about 12 hours after the original buccal system was applied.

    If Striant falls off after 8 hours but before 12 hours, replace the original buccal system. This replacement can serve as the second dose for that day.

    It is fine if Striant sticks to your cheek and not your gum. Do not replace the buccal system if this should happen. Check to see if Striant is in place after toothbrushing, using mouthwash, and eating or drinking. If Striant does not stick or falls off, follow the above mentioned directions to replace with a new system.

  • What should I avoid while taking Striant?

    Striant should not be chewed or swallowed.

    Do not give Striant to other people, even if they have the same symptoms you have. It may harm them; Striant is a controlled substance with the potential for abuse and may lead to moderate or low physical dependence or high psychological dependence.

    Do not use damaged blister packs.

  • What are possible food and drug interactions associated with Striant?

    If Striant is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Striant with the following: corticosteroids such as prednisone, insulin, and oxyphenbutazone.

  • What are the possible side effects of Striant?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: liver problems such as jaundice (a yellowing of the whites of your eyes, dark urine, pale bowel movements, loss of appetite, nausea, lower abdominal pain, problems urinating, fluid retention in your ankles and legs, fast weight gain, penile erections that are painful, occur too frequently, or that last for too long, enlarged breasts, emotional changes such as depression, enlarged prostate, prostate cancer, gingivitis (usually temporary), taste distortion, bitter taste, headache, gum problems (e.g, redness swelling, irritation, pain, or tenderness), headache

  • Can I receive Striant if I am pregnant or breastfeeding?

    Striant is not for use in women, especially those that are pregnant or breastfeeding. Striant may harm the babies of pregnant and breastfeeding women.

  • What should I do if I miss a dose of Striant?

    If you miss a dose, just begin again with your next scheduled dose. Do not try to make up for your missed dose.

    If Striant does not stick or falls off within the first 8 hours, remove the original system and apply a new one. This counts as replacing the first dose. Apply the next system about 12 hours after the original buccal system was applied. If Striant falls off after 8 hours but before 12 hours, replace the original buccal system. This replacement can serve as the second dose for that day.

  • How should I store Striant?

    Store at room temperature and protect from heat and moisture. Do not use damaged blister packs.

    Discard Striant buccal systems safely so children or pets cannot accidentally access them.

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

Check out my latest post on cholesterol drugs.

Striant Related Drugs

Striant Related Conditions