Sulfamylon Solution

Generic Name: Mafenide

  • What is Sulfamylon Solution?

    Sulfamylon Solution is a topical solution (applied directly on the skin) that is used to prevent bacterial infections in people with burn wounds who have undergone skin grafts.

  • What is the most important information I should know about Sulfamylon Solution?

    Sulfamylon Solution is for external use only.

    Sulfamylon Solution can cause hemolytic anemia (a blood disorder in which red blood cells are destroyed) with a certain blood clotting disorder, especially in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency (lack of an enzyme responsible for the breakdown of red blood cells). Tell your doctor if you have G6PD deficiency.

    If you have lung or kidney impairment, you are at a higher risk of developing an abnormality of the normal balance of acids and bases in your body if you use Sulfamylon Solution. Your doctor will monitor you for this imbalance. Tell your doctor if you experience abnormally rapid breathing.

  • Who should not take Sulfamylon Solution?

    Do not use Sulfamylon Solution if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Sulfamylon Solution?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Sulfamylon Solution. Also, talk to your doctor about your complete medical history, especially if you have lung or kidney problems, or G6PD deficiency.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥3 months: Apply the solution to the affected area(s) using an irrigation syringe or tubing every 4 hours or as needed to keep your wound wet. If you do not use an irrigation syringe or tube, moisten the gauze every 6-8 hours or as needed to keep your wound wet.

  • How should I take Sulfamylon Solution?

    Apply Sulfamylon Solution exactly as prescribed by your doctor. Cover grafted area with mesh gauze. Wet the gauze with the solution to keep it wet. You can use the solution for up to 5 days with the same dressing.

  • What should I avoid while taking Sulfamylon Solution?

    Do not ingest Sulfamylon Solution by mouth.

  • What are possible food and drug interactions associated with Sulfamylon Solution?

    No significant interactions have been reported with Sulfamylon Solution at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Sulfamylon Solution?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: blisters, blood problems, breathing difficulties, burning sensation, facial swelling, itching, pain, rash, redness, softening of your skin

  • Can I receive Sulfamylon Solution if I am pregnant or breastfeeding?

    The effects of Sulfamylon Solution during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Sulfamylon Solution?

    Sulfamylon Solution should be given under special circumstances determined by your doctor.

  • How should I store Sulfamylon Solution?

    Store in a dry place at room temperature. After mixing, store the solution for up to 28 days, and once the container is opened, discard any unused solution within 48 hours.