Generic Name: Trimipramine

  • What is Surmontil?

    Surmontil is a tricyclic antidepressant medication used to treat depression.

  • What is the most important information I should know about Surmontil?

    Antidepressant medicines, like Surmontil, may increase suicidal thoughts or actions in some children, teenagers, and young adults when the medicine is first started. People with bipolar disorder, or who have a family history of this condition (also called manic-depressive illness), are at a greater risk.

    Call your doctor immediately if new symptoms develop or seem to get worse. Signs to watch for include anxiety, hostility, insomnia, restlessness, impulsive or dangerous behavior, and thoughts about suicide or dying.

    Never stop an antidepressant medication without first talking to your doctor. Abruptly stopping Surmontil can cause other symptoms.

  • Who should not take Surmontil?

    Do not use Surmontil if you are allergic to it or any of its ingredients.

    Do not take Surmontil if you are taking an antidepressant drug in a class called monoamine oxidase inhibitors (MAOIs) such as phenelzine, tranylcypromine, and isocarboxazid or if you have stopped taking an MAOI in the last 14 days.

    Do not take Surmontil if you have recently had a heart attack.

  • What should I tell my doctor before I take the first dose of Surmontil?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Surmontil. Also, talk to your doctor about your complete medical history, especially if you have a family history of suicide, bipolar disorder, or depression. Also, let your doctor know if you have a history of diabetes; glaucoma (increased pressure in the eye); heart, kidney, or liver disease; overactive thyroid; seizure disorder; or urinary retention.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is 75 milligrams (mg) per day, divided into equal, smaller doses. Your doctor may gradually increase your dose to 150 mg per day, again, divided into smaller doses.

    Elderly or adolescents: Dosages usually start at 50 mg per day. Your doctor may increase the dose to 100 mg a day, if needed.

  • How should I take Surmontil?

    Surmontil should be taken exactly as prescribed by your doctor.

    Do not stop taking Surmontil if you feel no immediate effect it may take up to 4 weeks for its benefits to appear.

    Surmontil can cause dry mouth. Sucking hard candy or chewing gum can help this problem.

  • What should I avoid while taking Surmontil?

    Avoid driving a car, operating machinery, or participating in any activities that require full alertness if you are not sure of the drug's effect on you. Avoid using alcohol, which may increase drowsiness and dizziness while taking Surmontil.

    Surmontil may increase your skin's sensitivity to sunlight. Avoid direct sunlight, wear protective clothing, and apply sun block (minimum SPF 15).

  • What are possible food and drug interactions associated with Surmontil?

    If Surmontil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Surmontil with the following: antidepressants; antispasmodic drugs such as benztropine and atropine; cimetidine; decongestants; drugs for heart irregularities such as flecainide and propafenone; epinephrine; guanethidine; quinidine; tranquilizers; and thyroid medications.

  • What are the possible side effects of Surmontil?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, black tongue, blood disorders, blurred vision, breast development in men, confusion, dizziness, drowsiness, dry mouth, heartbeat irregularities, high or low blood pressure, insomnia, lack of coordination, stomach and intestinal problems, urination problems, vomiting, weight changes

  • Can I receive Surmontil if I am pregnant or breastfeeding?

    The effects of Surmontil during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Surmontil?

    If you miss a dose of Surmontil, take it soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Surmontil?

    Store at room temperature.