Surmontil

Generic Name: Trimipramine maleate

  • What is Surmontil?

    Surmontil is a tricyclic antidepressant used to treat depression.
  • What is the most important information I should know about Surmontil?

    Never take Surmontil if you are taking an antidepressant drug called a monoamine oxidase inhibitor (MAOI) or if you have stopped taking an MAOI in the last 14 days. MAOI drugs include phenelzine, tranylcypromine, and isocarboxazid. Taking Surmontil close in time to an MAOI can result in serious—sometimes fatal—reactions, including high body temperature, coma, and seizures.

    Antidepressants can increase the risk of suicidal thinking and behavior in children and teenagers. Adult and pediatric patients taking antidepressants should be watched closely for changes in moods or actions, especially when they first start therapy or when their dose is increased or decreased. Patients and their families should contact the doctor immediately if new symptoms develop or seem to get worse. Signs to watch for include anxiety, hostility, insomnia, restlessness, impulsive or dangerous behavior, and thoughts about suicide or dying.

    Never stop an antidepressant medication without first talking to your healthcare provider. Abruptly stopping Surmontil can cause other symptoms.

    Antidepressant medications have other side effects. Talk to your healthcare provider about the side effects of the medicine prescribed for you or your family member.

  • Who should not take Surmontil?

    Surmontil should not be used if you are recovering from a recent heart attack or if you are sensitive to the drug.
  • What should I tell my doctor before I take the first dose of Surmontil?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Surmontil. Also, talk to your doctor about your complete medical history, especially if you have a family history of suicide, bipolar disorder, or depression. Also let your doctor know if you have a history of diabetes; glaucoma (increased pressure in the eye); heart, kidney, or liver disease; overactive thyroid; seizure disorder; or urinary retention.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is 75 milligrams (mg) per day, divided into equal, smaller doses. Your doctor may gradually increase your dose to 150 mg per day, again, divided into smaller doses. Doses over 200 mg a day are not recommended. Doses for long-term therapy may range from 50 to 150 mg daily. You can take this total daily dosage at bedtime or spread it throughout the day.

    Elderly or adolescents: Dosages usually start at 50 mg per day. Your doctor may increase the dose to 100 mg a day, if needed.

    Surmontil is not approved for use in children.

  • How should I take Surmontil?

    Surmontil is taken by mouth. Many people take one dose at bedtime. Others may find it works better to take Surmontil more than once a day.

    It is important to take Surmontil exactly as prescribed, even if the drug seems to have no effect. It may take up to 4 weeks for its benefits to appear.

    Surmontil can make your mouth dry. Sucking hard candy or chewing gum can help this problem.

  • What should I avoid while taking Surmontil?

    Avoid driving a car, operating machinery, or participating in any activities that require full alertness if you are sure of the drug's effect on you.

    Avoid using alcohol, which may increase drowsiness and dizziness while taking Surmontil.

  • What are possible food and drug interactions associated with Surmontil?

    If Surmontil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Surmontil with the following: antidepressants, antispasmodic drugs such as benztropine, atropine, cimetidine, decongestants, drugs for heart irregularities such as flecainide and propafenone, epinephrine, guanethidine, quinidine, tranquilizers, and thyroid medications.
  • What are the possible side effects of Surmontil?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, black tongue, blood disorders, blurred vision, breast development in men, confusion, dizziness, drowsiness, dry mouth, fluctuations in blood pressure, heartbeat irregularities, high or low blood pressure, insomnia, lack of coordination, stomach and intestinal problems, urination problems, vomiting

  • Can I receive Surmontil if I am pregnant or breastfeeding?

    The effects of Surmontil during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding. There is no information on whether Surmontil appears in breast milk. The doctor may tell you to stop breastfeeding until your treatment is finished.
  • What should I do if I miss a dose of Surmontil?

    Take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and go back to your regular schedule. Do not take two doses at once. If you take Surmontil once a day at bedtime and you miss a dose, do not take it in the morning; it could cause disturbing side effects during the day.
  • How should I store Surmontil?

    Store at room temperature in a tightly closed container, away from moisture.