What is Sutent?Sutent is used to treat gastrointestinal stromal tumors (GIST) if treatment with imatinib mesylate (Gleevec) therapy does not work or if you cannot take imatinib mesylate. Sutent is also used for the treatment of advanced kidney cancer.
What is the most important information I should know about Sutent?Sutent may harm an unborn baby. If you do become pregnant while taking Sutent, stop taking the drug and tell your doctor right away.
Who should not take Sutent?Do not take Sutent if you are allergic to sunitinib malate or any of its other ingredients. Also, do not take Sutent if you are pregnant or planning to become pregnant.
What should I tell my doctor before I take the first dose of Sutent?Tell your doctor about all prescription, over-the-counter and herbal medications you are using to avoid a possible interaction with Sutent. Also, talk to your doctor about your entire medical history, especially if you are pregnant, could be pregnant, or plan to become pregnant or are breastfeeding, have any heart problems, high blood pressure, kidney function problems (other than cancer), liver problems, or any bleeding problem or seizures.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: For both GIST and kidney cancer, the usual dose of Sutent is one 50-milligram (mg) capsule taken once a day, on the schedule of 4 weeks of treatment followed by 2 weeks off.
How should I take Sutent?Sutent comes in 12.5-mg, 25-mg, and 50-mg capsules. Do not open the capsules. Take Sutent once a day with or without food. Take it exactly the way your doctor tells you.
What should I avoid while taking Sutent?While taking Sutent, avoid pregnancy and breastfeeding.
Do not drink grapefruit juice or eat grapefruit. Do not take St. John's wort while taking Sutent.
What are possible food and drug interactions associated with Sutent?If Sutent is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sutent with the following: atazanavir, carbamazepine, clarithromycin, dexamethasone, grapefruit, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, phenobarbital, phenytoin, rifabutin, rifampin, rifapentin, ritonavir, saquinavir, St. John's wort, telithromycin, and voriconizole.
What are the possible side effects of Sutent?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, bleeding, constipation, diarrhea, feeling tired, heart problems, high blood pressure, stomach or bowel wall perforation, lightened hair, loss of appetite, mouth sores, nausea, skin abnormalities, swelling, taste changes, upset stomach, vomiting
Can I receive Sutent if I am pregnant or breastfeeding?Do not take Sutent if you are pregnant, planning to become pregnant, or are breastfeeding. This drug may cause severe abnormalities or even death in your unborn child.
What should I do if I miss a dose of Sutent?Take it as soon as you remember. Do not take if it is close to your next dose. Just take the next dose at your regular time. Do not take two doses at one time. Tell your doctor about the missed dose.
How should I store Sutent?Store at room temperature.
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