Generic Name: Lidocaine and tetracaine

  • What is Synera?

    Synera is a topical anesthetic patch used to locally numb regions of skin for a procedure such as a biopsy or to gain access into a vein with a needle.
  • What is the most important information I should know about Synera?

    Leaving a Synera patch on longer than recommended may result in a severe overdose of lidocaine/tetracaine. Only use Synera for the time recommended by your doctor.

    Even used Synera patches contain large amounts of lidocaine/tetracaine; store and dispose of the patches out of the reach of children and pets.

  • Who should not take Synera?

    Do not use Synera if you are allergic to lidocaine/tetracaine, or have had allergic reactions to other topical anesthetics. Also, patients that have an allergy to a compound known as PABA should not use Synera.
  • What should I tell my doctor before I take the first dose of Synera?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking. Also, talk to your doctor about your complete medical history.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Apply the Synera patch to unbroken, nonirritated skin as directed by your doctor.

  • How should I take Synera?

    Apply the patch immediately after opening its pouch.

    For use with an IV line, apply the patch for 20 to 30 minutes before the IV line is to be inserted. For a procedure on the skin, such as a biopsy, Synera patch will be applied 30 minutes before the procedure begins.

    If irritation occurs while Synera is on your skin, remove the patch immediately.

  • What should I avoid while taking Synera?

    Avoid applying the Synera patch to broken or irritated skin. Doing so may result in a toxic reaction. Do not cut the patch.
  • What are possible food and drug interactions associated with Synera?

    If Synera is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Synera with other local anesthetics and antiarrhythmic drugs such as tocainide and mexiletine.
  • What are the possible side effects of Synera?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: irritation or redness of the skin, swelling, whitening of the skin

  • Can I receive Synera if I am pregnant or breastfeeding?

    Talk to your doctor if you are pregnant, planning to become pregnant, or are nursing. Synera has not been adequately studied to know its effect during pregnancy. However, it does pass into breast milk, so caution should be used during breastfeeding. Follow your doctor's instructions.
  • What should I do if I miss a dose of Synera?

    Synera is only used once for specific purposes and does not follow a dosing regimen.
  • How should I store Synera?

    Store at room temperature. The used patch should be disposed of immediately. The adhesive sides of the patch should be folded together and the patch should then be thrown away in a location that is out of the reach of children and pets.