Generic Name: Dalfopristin

  • What is Synercid?

    Synercid is an antibiotic used to treat certain complicated bacterial infections of the skin. It may also be used to treat other bacterial infections, as determined by your doctor. Synercid is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Synercid?

    Synercid can cause diarrhea or colitis (inflammation of the colon). This can occur a couple of months after receiving the last dose of Synercid. Tell your doctor immediately if you have diarrhea or colitis.

    Synercid can cause severe muscle or joint pain. Tell your doctor if you develop any of these symptoms.

  • Who should not take Synercid?

    Your doctor will not administer Synercid to you if you are allergic to it, any of its ingredients, or similar antibiotics (such as pristinamycin or virginiamycin).

  • What should I tell my doctor before I take the first dose of Synercid?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Synercid. Also, talk to your doctor about your complete medical history, especially if you have allergies or liver problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥12 years: Your doctor will administer the appropriate dose for you based on your weight and condition.

    If you have liver impairment, your doctor will adjust your dose appropriately.

  • How should I take Synercid?

    Your doctor will administer Synercid for you.

  • What should I avoid while taking Synercid?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Synercid?

    If Synercid is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with Synercid: anti-cancer agents (such as docetaxel, paclitaxel, or vinblastine); antihistamines (such as astemizole or terfenadine); anti-HIV medications (such as delavirdine, indinavir, nevirapine, or ritonavir); benzodiazepines (such as diazepam or midazolam); cholesterol-lowering medications (such as lovastatin); cisapride; cyclosporine; heart/blood pressure medications known as calcium channel blockers (such as diltiazem, nifedipine, or verapamil); or tacrolimus.

  • What are the possible side effects of Synercid?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, headache, injection-site reactions (such as inflammation or swelling), itchiness, nausea, pain, rash, vomiting

  • Can I receive Synercid if I am pregnant or breastfeeding?

    The effects of Synercid during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Synercid?

    Synercid should be given under special circumstances determined by your doctor.

  • How should I store Synercid?

    Your doctor will store this medication for you.