Generic Name: Temozolomide

  • What is Temodar?

    Temodar is used to treat adults with certain brain tumors. Temodar blocks cell growth, especially in cells that grow fast, such as cancer cells.

  • What is the most important information I should know about Temodar?

    Temodar may cause birth defects. Women should not become pregnant while using this drug. Both men and women who take Temodar should use effective birth control. In addition, female partners of men using Temodar should avoid becoming pregnant.

  • Who should not take Temodar?

    Do not take Temodar if you have had an allergic reaction to any of its ingredients or to DTIC (dacarbazine), another cancer medicine. Temodar has not been studied in children.

  • What should I tell my doctor before I take the first dose of Temodar?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Temodar. Also, talk to your doctor about your complete medical history, especially if you are allergic to any medication, have kidney or liver problems, or you are pregnant, planning to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will determine the dose based on your weight, condition, and other treatments you are receiving (e.g., radiation). The number of treatment cycles will depend on how you respond to Temodar therapy.

  • How should I take Temodar?

    Temodar may be taken by mouth as a capsule at home, or you may receive Temodar by injection into a vein (intravenous). Your doctor will decide the best way for you to take Temodar.

    If you are taking Temodar capsules, your doctor will provide instructions on how many to take and at what time. Swallow Temodar capsules whole. Do not chew, open, or split the capsules. If Temodar capsules are accidentally opened or damaged, be careful not to breathe in the powder from the capsules or get the powder on your skin or mucous membranes (for example, in your nose or mouth). If contact with any of these areas happens, flush the area with water. If you vomit after taking the medication, do not take any more capsules. Wait and take your next planned dose.

  • What should I avoid while taking Temodar?

    Women using Temodar should avoid becoming pregnant, and female partners of men using Temodar should also avoid becoming pregnant.

  • What are possible food and drug interactions associated with Temodar?

    If Temodar is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Temodar with valproic acid (e.g., Stavzor or Depakene).

  • What are the possible side effects of Temodar?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: nausea and vomiting; headache; feeling tired; loss of appetite; hair loss; constipation; bruising; rash; paralysis on one side of the body; diarrhea; weakness; fever; dizziness; coordination problems; viral infection; sleep problems; memory loss; pain, irritation, itching, warmth, swelling, or redness at the site of infusion; bruising or small red or purple spots under the skin

    Serious side effects may include: decreased blood cells, a serious lung infection known as Pneumocystis carinii pneumonia (PCP), secondary cancers, convulsions

  • Can I receive Temodar if I am pregnant or breastfeeding?

    Temodar can harm your unborn baby if taken during pregnancy. You should avoid becoming pregnant while taking this drug. The effects of Temodar during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Temodar?

    If you miss a dose of Temodar, talk with your doctor about when to take the next dose. This will help to prevent taking too much Temodar and decrease your chances of having serious side effects.

  • How should I store Temodar?

    Store Temodar capsules at room temperature. Your doctor will store the injection.

Meet the Pharmacists

I'm Kristen Dore, PharmD. Welcome to PDR Health!

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