Generic Name: Chlorthalidone

  • What is this medication and its most common uses?

    Tenoretic is a medicine used to treat high blood pressure. Tenoretic contains two medicines that work in two different ways to reduce your blood pressure: atenolol and chlorthalidone.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Atenolol works by decreasing your heart rate, and relaxing and widening your blood vessels, allowing your blood to flow through with less resistance. Chlorthalidone is a water pill and works by eliminating extra fluid and sodium (salt) from your body. Together, they help to lower your blood pressure.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: By lowering your blood pressure, Tenoretic may lower your risk of a stroke or a heart attack.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider will also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: tiredness, dizziness, cold hands and feet.

    Less common side effects may include:

    Changes in electrolytes (chemicals that are important for the cells in your body to function, such as sodium and potassium) with symptoms such as dry mouth, thirst, weakness, tiredness, drowsiness, restlessness, muscle pains or cramps, muscle tiredness, dizziness or fainting, low or no urine output, fast heartbeat, or nausea and vomiting.

    Breathing problems or worsened heart failure with symptoms such as weight gain, increased shortness of breath, or a slow heartbeat.

    Tenoretic may hide symptoms of low blood sugar levels if you have diabetes.

    Tenoretic may harm your unborn baby if you take it during pregnancy. Tell your healthcare provider if you become pregnant while you are taking Tenoretic.

  • Who should not take this medication?

    Do not take Tenoretic if you are allergic to it, any of its ingredients, or other sulfonamide medications (such as sulfamethoxazole).

    Do not take Tenoretic if you have certain heart problems (such as heart failure, a slow heartbeat, or your heart skips a beat).

    Do not take Tenoretic if you are unable to produce urine.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tenoretic. Also, talk to your healthcare provider about your complete medical history, especially if you have lung problems (such as bronchitis or emphysema); problems with blood flow in your feet and legs; pheochromocytoma (tumor of the adrenal gland); diabetes; lupus (a disease that affects the immune system); liver, kidney, or thyroid problems; if you are scheduled for surgery; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    Tell your healthcare provider if you have a history of severe allergic reactions to any allergens, because Tenoretic may decrease the effectiveness of epinephrine, a medicine used to treat such reactions.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended starting dose is 50/25 (50 milligrams [mg] of atenolol and 25 mg of chlorthalidone) once a day. Your healthcare provider may increase your dose as needed until the desired effect is achieved.

    If you have kidney impairment, your healthcare provider may adjust your dose appropriately.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Tenoretic exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Tenoretic without first talking to your healthcare provider.

  • What should I avoid while taking this medication?

    Do not drive a car, operate machinery, or engage in other tasks requiring alertness until you know how Tenoretic affects you.

  • What are the possible food and drug interactions associated with this medication?

    If Tenoretic is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Tenoretic with the following: amiodarone, blood pressure/heart medications known as calcium channel blockers (such as diltiazem and verapamil), clonidine, digoxin, disopyramide, lithium, muscle relaxants (such as tubocurarine), nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen and indomethacin), norepinephrine, or reserpine.

  • May I receive this medication if I am pregnant or breastfeeding?

    Tenoretic can harm your unborn baby if you take it during pregnancy. Tenoretic can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Tenoretic, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

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