Generic Name: Somatropin

  • What is Tev-Tropin?

    Tev-Tropin is a medicine that contains human growth hormone. It is used as a replacement for natural growth hormone in children with growth failure due to growth hormone deficiency (GHD). Tev-Tropin is administered subcutaneously (just below the skin).

  • What is the most important information I should know about Tev-Tropin?

    While your child is on Tev-Tropin, increased pressure in his/her brain can occur, and may include papilledema (swelling of the optic disk), visual changes, headache, nausea, and/or vomiting.

    If your child has tumors or lesions in the brain, he/she should be monitored for worsening or recurrence of the tumor or lesions. In addition, Tev-Tropin can cause a second tumor, especially in your child's brain after receiving radiation to his/her head for the first tumor.

    Tev-Tropin can increase your child's blood sugar levels. Check his/her blood sugar levels regularly. The doctor may need to adjust the dose of your child's diabetes medications.

    Tev-Tropin can cause pancreatitis (inflammation of the pancreas). Tell the doctor if your child experiences abdominal pain while using Tev-Tropin.

    Tev-Tropin can also cause or worsen hypothyroidism (an underactive thyroid gland), and in children can cause a progression of scoliosis (curving of the spine).

    Slip of the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth. Tell your doctor if your child experiences limping or pain in his/her knee or hip.

    Tev-Tropin can be reconstituted with Bacteriostatic Water for Injection, which contains benzyl alcohol as a preservative. Benzyl alcohol can cause toxicity in your newborn baby. You can use Sterile Normal Saline for Injection, but you can use only one dose per vial and discard the unused portion.

  • Who should not take Tev-Tropin?

    Do not use Tev-Tropin if your child is allergic to it, any of its ingredients, or benzyl alcohol if you are mixing Tev-Tropin with Bacteriostatic Water for Injection. Also, do not use Tev-Tropin if your child has eye problems caused by diabetes, active cancer, or your child is critically ill with severe breathing (respiratory) problems or with complications following heart or abdominal surgery, or trauma.

  • What should I tell my doctor before I take the first dose of Tev-Tropin?

    Tell the doctor about all prescription, over-the-counter, and herbal medications your child is taking before beginning treatment with Tev-Tropin. Also, talk to the doctor about your child's complete medical history, especially if he/she have a serious medical condition after having an open heart or abdominal surgery, serious injuries involving many body systems, or breathing problems (such as sudden respiratory failure), cancer or other tumors, multiple hormone deficiencies, pancreatitis, hypothyroidism, scoliosis, or diabetes.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Children: Your doctor will prescribe the appropriate dose for your child, based on their weight.

  • How should I take Tev-Tropin?

    Use Tev-Tropin exactly as prescribed by the doctor.

    Change the sites of injection every day to avoid injection-site reactions (such as bruising, redness, or pain).

    The doctor will show you and/or your caregiver how to inject this medicine, as well as how to properly dispose syringes and needles. Please review the instructions that came with the prescription on how to properly use Tev-Tropin.

  • What should I avoid while taking Tev-Tropin?

    After mixing, do not shake the solution, and do not inject the solution if cloudiness persists or particles are noted.

    Do not reuse needles and syringes.

  • What are possible food and drug interactions associated with Tev-Tropin?

    If Tev-Tropin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with the doctor before combining Tev-Tropin with the following: cyclosporine, diabetes medications, glucocorticoids (such as prednisone), insulin, seizure medications, or sex steroids (such as estrogen, progesterone, or testosterone).

  • What are the possible side effects of Tev-Tropin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: breast enlargement, headache, high blood sugar levels, injection-site reactions

  • Can I receive Tev-Tropin if I am pregnant or breastfeeding?

    Tev-Tropin is intended for use only by children. The effects of Tev-Tropin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Tev-Tropin?

    If your child misses a dose of Tev-Tropin, inject it as soon as you remember. However, if it is almost time for the next dose, skip the one missed and return to the regular dosing schedule. Do not inject two doses at once.

  • How should I store Tev-Tropin?

    Store in the refrigerator. After mixing, use the vial within 14 days. Do not freeze.