Generic Name: Chlorthalidone

  • What is Thalitone?

    Thalitone is a diuretic (water pill) used to treat high blood pressure alone or with other blood pressure medications. Thalitone, in combination with other medications, also treats fluid retention associated with congestive heart failure, cirrhosis of the liver (a disease of the liver), corticosteroid and estrogen therapy, and kidney disease.

  • What is the most important information I should know about Thalitone?

    Thalitone may cause your body to lose potassium. Contact your doctor if you experience great thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

    Keep all follow-up visits with your doctor. Your doctor will need to periodically monitor the levels of electrolytes in the blood.

    Avoid taking alcohol as it may increase the chance of experiencing dizziness.

  • Who should not take Thalitone?

    Do not take Thalitone if you are unable to urinate or if you have ever had an allergic reaction to, or are sensitive to, Thalitone or other sulfonamide drugs.

  • What should I tell my doctor before I take the first dose of Thalitone?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Thalitone. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver disease, a history of allergies, have a history of allergic reaction to chlorthalidone or other water pills, have asthma, lupus (a chronic condition that affects your immune system), gout, diabetes, are pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    High Blood Pressure

    Adults: The usual starting dose of Thalitone is 15 milligrams (mg) once daily. Your doctor may increase your dose to 30 mg and then to 45-50 mg once daily. If your blood pressure is still not well managed after 50 mg once daily, a second blood pressure drug is required.

    Fluid Retention

    Adults: The usual starting dose of Thalitone is 30-60 mg daily or 60 mg every other day. Your doctor may increase the dose to 90-120 mg at these intervals. Your doctor may be able to lower the dose as treatment continues.

  • How should I take Thalitone?

    Take Thalitone exactly as prescribed. Your doctor may recommend taking it in the morning, with food.

  • What should I avoid while taking Thalitone?

    Thalitone may cause dizziness. Use caution when driving, operating machinery, or performing other hazardous activities.

    Avoid drinking alcohol. Alcohol may increase the chance of dizziness occurring.

    Avoid prolonged exposure to sunlight or UV light (tanning beds). Thalitone may increase the sensitivity of your skin to sunlight. Wear sunscreen and protective clothing when you are outside.

  • What are possible food and drug interactions associated with Thalitone?

    If Thalitone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Thalitone with any of the following: blood pressure medications, digoxin, insulin, lithium, norepinephrine, oral diabetes medications, and tubocurarine.

  • What are the possible side effects of Thalitone?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: anemia, changes in blood sugar, low potassium levels (e.g., symptoms may include great thirst, tiredness, drowsiness, restlessness, muscle pains, nausea, or increased heart rate or pulse), constipation, cramping, diarrhea, dizziness, headache, impotence, inflammation of the pancreas, loss of appetite, low blood pressure, muscle spasms, nausea, rash, restlessness, sensitivity to light, stomach irritation, vomiting, weakness, yellow eyes and skin

  • Can I receive Thalitone if I am pregnant or breastfeeding?

    The effects of Thalitone during pregnancy are unknown. Thalitone is found in human milk. Because serious side effects may occur in the infant, you and your doctor should decide whether to discontinue breastfeeding or discontinue the drug, taking into account the importance of using Thalitone. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Thalitone?

    If you miss a dose of Thalitone, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.

  • How should I store Thalitone?

    Store at room temperature.

Starting a Cholesterol Drug?

Our seven-week newsletter series, written by a pharmacist, will help you learn about your medication.
Sign Up

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

Check out my latest post on cholesterol drugs.

Thalitone Related Drugs