Theophylline extended-release

Generic Name: Theophylline

  • What is Theophylline extended-release?

    Theophylline extended-release (ER) is a medicine used to treat symptoms associated with long-term asthma and other lung diseases, such as emphysema (lung disease that causes shortness of breath) and chronic bronchitis (long-term inflammation of the lungs).

  • What is the most important information I should know about Theophylline extended-release?

    Your doctor will monitor your blood theophylline levels and will adjust your dose of theophylline ER appropriately.

    Your blood theophylline levels can increase if you take theophylline ER while you have heart diseases, such as heart failure or cor pulmonale (right-sided heart failure); persistent fever; hypothyroidism (an underactive thyroid gland); liver disease, such as cirrhosis (scarring of the liver) or hepatitis; kidney impairment in infants <3 months; sepsis (a bloodstream infection) with failure of multiple organs; shock; or cessation of smoking. Tell your doctor if you have any of these conditions, and he/she will decrease your total daily dose of theophylline ER appropriately.

    Tell your doctor if you develop symptoms of theophylline toxicity (such as nausea, vomiting, persistent headache, insomnia, or rapid heartbeat) while you are taking theophylline ER.

    Theophylline ER can worsen stomach ulcers, seizures, and arrhythmias (life-threatening irregular heartbeats). Tell your doctor if you have any of these conditions.

    Tell your doctor if you develop a new illness, worsening of a long-term illness, start or stop smoking cigarettes or marijuana, start a new medication, or stop using any of your previously prescribed medications while you are taking theophylline ER.

    Do not be concerned if a tablet is present in your stool, because theophylline ER tablets have a matrix that the body does not absorb.

  • Who should not take Theophylline extended-release?

    Do not take theophylline ER if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Theophylline extended-release?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with theophylline ER. Also, talk to your doctor about your complete medical history, especially if you have certain heart diseases, swelling in your lungs, stomach ulcer, seizures, fever, thyroid problems, liver or kidney problems, or cystic fibrosis (inherited disease that causes your mucus to be thick and sticky, and may result in difficulty breathing).

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children 12-15 years and >45 kg: The recommended starting dose is 300-400 milligrams (mg) every 24 hours. Your doctor will prescribe the appropriate dose for you and will increase your dose as needed, until the desired effect is achieved.

    Children 12-15 years and <45 kg: Your doctor will prescribe the appropriate dose for your child, based on their weight.

  • How should I take Theophylline extended-release?

    Take theophylline ER exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor. Take theophylline ER in the morning or evening. It is recommended to take this medication with meals consistently. If you choose to eat this without food, it should be taken without food consistently.

  • What should I avoid while taking Theophylline extended-release?

    Do not chew or crush theophylline ER tablets.

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Theophylline extended-release?

    If theophylline ER is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Theophylline ER may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.

  • What are the possible side effects of Theophylline extended-release?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: arrhythmia, diarrhea, headache, increased urination, insomnia, irritability, nausea, rapid heartbeat, restlessness, seizure, tremor, vomiting

  • Can I receive Theophylline extended-release if I am pregnant or breastfeeding?

    The effects of theophylline ER during pregnancy are unknown. Theophylline ER is excreted into breast milk and may cause irritability in nursing infants. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Theophylline extended-release?

    If you miss a dose of theophylline ER, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Theophylline extended-release?

    Store at room temperature.