Generic Name: Tobramycin

  • What is Tobi?

    Tobi is an antibiotic used to manage a specific bacterial infection in people with cystic fibrosis (inherited disease that causes your mucus to be thick and sticky, and may result in difficulty breathing). Tobi is available in a solution for inhalation.

  • What is the most important information I should know about Tobi?

    Tobi can cause harm to your nervous system, including problems with your hearing and balance. This can also cause numbness, skin tingling, muscle twitching, or seizures. Your risk can increase with impaired kidney function. Tell your doctor immediately if you experience dizziness, ringing or roaring in your ear, or any changes in your hearing.

    Tobi can cause kidney problems. Your doctor will monitor your kidney function. Tell your doctor if you experience a decrease in urination.

    Tobi can harm your unborn baby if you use it during pregnancy. Tell your doctor immediately if you are pregnant or plan to become pregnant.

  • Who should not take Tobi?

    Do not take Tobi if you are allergic to it, any of its ingredients, or similar antibiotics (such as amikacin, neomycin, or streptomycin).

  • What should I tell my doctor before I take the first dose of Tobi?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tobi. Also, talk to your doctor about your complete medical history, especially if you have allergies; kidney disease; muscular disorders, such as myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness) or Parkinson's disease; or are pregnant or plan to become pregnant.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥6 years: The recommended dose is 300 milligrams (mg) every 12 hours for 28 days.

  • How should I take Tobi?

    Use Tobi exactly as prescribed by your doctor. Tobi is administered by inhalation using a nebulizer or an air compressor.

    Please review the instructions that came with your prescription on how to properly use Tobi.

  • What should I avoid while taking Tobi?

    Do not use Tobi with similar antibiotics that can cause hearing or kidney problems.

    Do not use Tobi if the solution is cloudy or contains particles.

  • What are possible food and drug interactions associated with Tobi?

    If Tobi is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tobi with the following: diuretics (water pills) (such as ethacrynic acid, furosemide, mannitol, or urea), dornase alfa (Pulmozyme), inhaled asthma medications (such as albuterol or fluticasone), or other similar antibiotics (such as amikacin, neomycin, or streptomycin).

  • What are the possible side effects of Tobi?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: bad taste in your mouth, breathing problems, changes in your voice, chest pain, cough, fever, headache, hearing loss, mucus discoloration or increase, ringing or roaring in your ear, runny nose, weakness

  • Can I receive Tobi if I am pregnant or breastfeeding?

    Tobi can harm your unborn baby if you use it during pregnancy. The effects of Tobi during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Tobi?

    If you miss a dose of Tobi, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Tobi?

    Store in the refrigerator, or at room temperature for up to 28 days. Protect from light.