Trazodone

Generic Name: Trazodone

  • What is Trazodone?

    Trazodone is a medicine used to treat depression.

  • What is the most important information I should know about Trazodone?

    Antidepressant medicines, like trazodone, may increase suicidal thoughts or actions in some children, teenagers, and young adults when the medicine is first started. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. People with bipolar disorder, or who have a family history of this condition (also called manic-depressive illness), are at a greater risk. Contact your doctor immediately if you experience any changes, especially sudden ones, in mood, behavior, thoughts, or feelings. Signs to watch for include new or worsening depression, new or worsening anxiety, agitation, insomnia, hostility, panic attacks, restlessness, extreme hyperactivity, and suicidal thinking or behavior. This is very important when an antidepressant medicine is first started or when the dose is changed.

    Trazodone may cause a decrease in blood pressure especially if you are also taking medications for your blood pressure. Your doctor may decrease the dose of your blood pressure medication.

    Trazodone may cause prolonged or inappropriate penile erection. If this occurs, stop taking trazodone and contact your doctor immediately.

    Trazodone may cause drowsiness and affect your mental and motor skills so do not drive or operate heavy machinery until you know how trazodone will affect you. Avoid alcohol while taking trazodone as it can worsen these side effects.

  • Who should not take Trazodone?

    Do not take Trazodone if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Trazodone?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with trazodone. Also, talk to your doctor about your complete medical history, especially if you have been diagnosed with bipolar disorder in the past, have or had any heart problems, are currently taking other antidepressants, are taking medications for high blood pressure, or are taking medications for erectile dysfunction. Also tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is 150 milligrams (mg) per day in divided doses. Your doctor may increase the dose by 50 mg per day every 3 to 4 days if needed. The maximum daily dose should not exceed 400 mg per day.

  • How should I take Trazodone?

    Take trazodone after a meal or light snack. If trazodone makes you feel too drowsy, take a major portion of the total daily dose at bedtime.

  • What should I avoid while taking Trazodone?

    Trazodone may cause drowsiness and affect your mental and motor skills so do not drive or operate heavy machinery until you know how trazodone will affect you. Avoid alcohol while taking trazodone as it can worsen these side effects.

  • What are possible food and drug interactions associated with Trazodone?

    If trazodone is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining trazodone with the following: carbamazepine, digoxin, indinavir, itraconazole, ketoconazole, monoamine oxidase inhibitors (MAOIs), nefazodone, phenytoin, ritonavir, warfarin.

  • What are the possible side effects of Trazodone?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: drowsiness, dry mouth, dizziness/lightheadedness, blurred vision, allergic skin reaction, swelling, headache, decreased blood pressure, tiredness, nausea, vomiting, weight loss or gain, diarrhea, muscle pain, nasal congestion

  • Can I receive Trazodone if I am pregnant or breastfeeding?

    The effects of trazodone during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Trazodone?

    If you miss a dose of trazodone, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Trazodone?

    Store at room temperature.

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