Treanda

Generic Name: Bendamustine hydrochloride

  • What is Treanda?

    Treanda is used to treat chronic lymphocytic leukemia. It is also used to treat indolent B-cell non-Hodgkin's lymphoma that has progressed during or within 6 months of treatment with a drug (or a regimen containing the drug) called Rituxan.
  • What is the most important information I should know about Treanda?

    Treanda can cause a reduction in white blood cells, platelets, and red blood cells. Treanda should not be taken during pregnancy as it can cause fetal harm.
  • Who should not take Treanda?

    Do not take Treanda if you have a known hypersensitivity to bendamustine or mannitol. Do not take Treanda if you are pregnant.
  • What should I tell my doctor before I take the first dose of Treanda?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Treanda. Also talk to your doctor about your complete medical history, especially if you have any known allergies to mannitol or bendamustine, are pregnant or breastfeeding.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Chronic Lymphocytic Lymphoma

    Adults: The dosage is 100 mg/m2 administered into the vein over 30 minutes on Days 1 and 2 of a 28-day cycle for up to 6 cycles.

    Indolent B-Cell non-Hodgkin's Lymphoma

    Adults: The dosage is 120 mg/m2 administered into the vein over 60 minutes on Days 1 and 2 of a 21-day cycle for up to 8 cycles.

  • How should I take Treanda?

    Treanda is administered intravenously (into the vein) in a hospital setting.
  • What should I avoid while taking Treanda?

    Avoid taking Treanda while pregnant. Avoid driving any vehicle or operating any machinery as Treanda cause tiredness.
  • What are possible food and drug interactions associated with Treanda?

    If taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Treanda with any other medications.
  • What are the possible side effects of Treanda?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions diarrhea, vomiting, fatigue, infections, skin reactions, tumor lysis syndrome (which can cause kidney failure and death), myelosuppression (bone marrow suppression)

    Signs of severe allergic reactions may include hives, difficulty breathing, and swelling of the throat. If any of these events occur, seek immediate medical attention.

  • Can I receive Treanda if I am pregnant or breastfeeding?

    Treanda should be avoided during pregnancy and breastfeeding.
  • What should I do if I miss a dose of Treanda?

    Treanda is administered in a hospital or office setting according to a strict schedule. Consult with your doctor if you think you would need to reschedule an appointment.
  • How should I store Treanda?

    Since Treanda is administered by your doctor, this is not an issue.