Generic Name: Fenofibrate

  • What is Triglide?

    Triglide is used in combination with diet and exercise to reduce LDL ("bad") cholesterol, total cholesterol levels, and triglycerides, and to increase HDL ("good") cholesterol.

  • What is the most important information I should know about Triglide?

    Triglide should be used in combination with a healthy diet and exercise to reduce cholesterol levels. Triglide should not be used with blood thinners or statins.

    Your doctor should regularly check your cholesterol levels, triglycerides, gallbladder, and liver function to monitor your progress to reach your target range of cholesterol levels, and prevent any harmful side effects.

    Treatment with Triglide should be discontinued if an adequate response is not obtained after 2 months of therapy at the maximal daily dose.

    The cholesterol medications atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin should be avoided in patients taking Triglide. Concurrent use of these medications may increase the likelihood of developing a serious side effect characterized by muscle pain, tenderness, and weakness.

    Triglide is not approved for use in children.

  • Who should not take Triglide?

    If you have kidney, liver, or gallbladder problems, or develop gallstones, do not take Triglide. Also, if you are allergic to one or more of the ingredients in Triglide, do not begin this type of cholesterol-lowering therapy.

  • What should I tell my doctor before I take the first dose of Triglide?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Triglide. Also, talk to your doctor about your complete medical history, especially if you have liver disease, gallbladder disease, gallstones, or severe kidney impairment.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    High Cholesterol Levels or a Combination of High Cholesterol and High Triglycerides

    Adults: The initial dose of Triglide is 160 milligrams (mg) per day.

    High Triglyceride Levels

    Adults: The starting dose of Triglide ranges from 50-160 mg per day.

    Adults ≥65 and those with kidney disorders: The starting dose of Triglide for older adults and those with poor kidney function is 50 mg per day and should be increased after evaluation of kidney function and cholesterol levels at higher doses.

    The maximum dose for Triglide is 160 mg a day. The dosage should be individualized according to the patient response, and should be adjusted if necessary following repeat cholesterol levels taken at 4- to 8-week intervals.

  • How should I take Triglide?

    Triglide may be taken with or without food, while following the diet and exercise plan as discussed with your doctor.

  • What should I avoid while taking Triglide?

    Do not start an exercise plan without talking to your doctor first.

  • What are possible food and drug interactions associated with Triglide?

    If Triglide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Triglide with blood thinners, cyclosporine, or other cholesterol-lowering medications known as statins.

  • What are the possible side effects of Triglide?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: back pain, chest pain, constipation, diarrhea, flu-like symptoms, nausea, headache, stomach pain, weakness

    Triglide may cause myopathy; signs of this condition include unexplained muscle pain, weakness, or tenderness. If you experience these symptoms, contact your doctor right away as this is a serious condition.

  • Can I receive Triglide if I am pregnant or breastfeeding?

    The effects of Triglide during pregnancy are unknown. Tell your doctor immediately if you are pregnant, or plan to become pregnant. Triglide should not be used in nursing mothers; therefore, a decision will need to be made whether to discontinue nursing or to discontinue Triglide.

  • What should I do if I miss a dose of Triglide?

    If you miss a dose of Triglide, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.

  • How should I store Triglide?

    Store at room temperature away from light and moisture.

Meet the Pharmacists

I'm Beth Isaac, PharmD. Welcome to PDR Health!

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