Trileptal

Generic Name: Oxcarbazepine

  • What is Trileptal?

    Trileptal helps reduce the frequency of partial epileptic seizures, a form of epilepsy in which neural disturbances are limited to a specific region of the brain and the victim remains conscious throughout the attack. Trileptal may be prescribed by itself to treat this problem in adults, or it can also be used in combination with other seizure medications in adults and children as young as 4 years old.
  • What is the most important information I should know about Trileptal?

    Trileptal can lead to a loss of sodium from the blood. This can result in a serious medical condition, which, if left untreated, could lead to convulsions, coma, and death. Your doctor should carefully monitor your blood sodium levels during treatment with Trileptal. Alert your doctor immediately if you develop warning signs such as nausea, headache, sluggishness, confusion, loss of feeling, or an increase in the frequency or severity of seizures.

    Serious skin reactions and severe allergic reactions have been reported in association with Trileptal use. If you develop a skin reaction or symptoms such as swelling of the face, eyes, lips, or tongue or difficulty in swallowing or breathing while using Trileptal, contact your doctor immediately.

    You should inform your doctor if you have used the epilepsy drug carbamazepine in the past. More than one quarter of patients who have had allergic reactions to carbamazepine may also experience allergic reactions to Trileptal.

  • Who should not take Trileptal?

    Do not take Trileptal if you are allergic to the medication or any or its ingredients.
  • What should I tell my doctor before I take the first dose of Trileptal?

    Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Trileptal. Also, talk to your doctor about your complete medical history, especially if you have kidney disease.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Trileptal Combined with Another Antiepileptic Medication

    Adults: The usual starting dose is 300 milligrams (mg) twice daily. Your doctor may increase the dose to 600 mg twice daily.

    Children 4 to 16 years old (dosage based on body weight): After a 2-week buildup, the dosage typically ranges from 450 to 900 mg taken twice daily.

    Trileptal Taken Alone

    Adults: The usual starting dose is 300 mg twice daily. Your doctor may gradually increase the dose to 600 mg twice daily. In people with kidney disorders, the starting dose is 150 mg twice daily.

    Children 4 to 16 years old (dosage based on body weight): Your child's doctor will gradually increase the dose every 3 days until the most effective dose is reached. The usual dose ranges from 300 to 1,050 mg taken twice daily.

    When Changing from Another Antiepileptic Medication to Trileptal

    Adults: The usual starting dose is 300 mg twice daily. Your doctor will gradually increase the Trileptal dose over a period of 2 to 4 weeks, while reducing the other medication over a period of 3 to 6 weeks. The final dosage of Trileptal is typically 1,200 mg twice daily.

    Children 4 to 16 years old (dosage based on body weight): Your child's doctor will gradually increase the dose of Trileptal while reducing the other medication over a period of 3 to 6 weeks. The doctor will increase the dose of Trileptal weekly until the most effective dose is reached. The usual dose ranges from 300 to 1,050 mg taken twice daily.

  • How should I take Trileptal?

    Take Trileptal exactly as prescribed by your doctor. If you stop taking Trileptal suddenly your seizures could become more frequent. You can take it with or without food.
  • What should I avoid while taking Trileptal?

    Trileptal can cause drowsiness, dizziness, and loss of coordination, which could impair your ability to drive a vehicle or operate dangerous machinery. Do not attempt hazardous activities until you know how the drug affects you.

    Alcohol consumption may increase sleepiness. Avoid drinking alcohol while you are taking Trileptal.

  • What are possible food and drug interactions associated with Trileptal?

    If Trileptal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Trileptal with any of the following: calcium channel blockers such as verapamil or felodipine, carbamazepine, phenobarbital, phenytoin, oral contraceptives, or valproic acid.
  • What are the possible side effects of Trileptal?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, abnormal vision, dizziness, double vision, fatigue, indigestion, lack of coordination, nausea, sleepiness, tremor, unusual and uncontrollable problems with walking, vomiting

  • Can I receive Trileptal if I am pregnant or breastfeeding?

    The effects of Trileptal during pregnancy are unknown. Tell your doctor immediately if you are pregnant, or plan to become pregnant.

    Trileptal appears in breast milk and could cause serious side effects in a nursing infant. Your doctor may make a choice between whether you should continue breastfeeding and continuing your Trileptal therapy.

  • What should I do if I miss a dose of Trileptal?

    Take it as soon as you remember. If it is almost time for your next dose, skip the dose you missed and go back to your regular schedule. Do not take 2 doses at once. If you miss more than one dose in a day, check with your doctor.
  • How should I store Trileptal?

    Store at room temperature in a tightly closed container.