Trilipix

Generic Name: Fenofibric acid

  • What is Trilipix?

    Trilipix is a cholesterol-lowering medicine used, in addition to an appropriate diet, to treat adults with high cholesterol. Trilipix reduces bad cholesterol (LDL-C), total cholesterol, triglycerides, and apolipoprotein B; and increases good cholesterol (HDL-C). It is also used, in combination with another cholesterol-lowering medicine known as statins (such as atorvastatin, fluvastatin, or pravastatin), to reduce triglycerides and increase HDL-C in patients with high cholesterol and high triglycerides.

  • What is the most important information I should know about Trilipix?

    Tell your doctor if you are taking any other medications while you are taking Trilipix. Trilipix may have an effect on medications that help prevent blood clotting (such as the blood thinner warfarin). If you are taking Trilipix with a blood thinner medication, your doctor will monitor your blood-clotting tests. Also, tell your doctor about any cholesterol-lowering medicines you may be taking as he or she will need to determine if the combination of Trilipix and one of those medications is right for you.

    Trilipix can cause liver problems. Your doctor will monitor your liver function.

    Trilipix can increase your risk of developing gallstones. Call your doctor immediately if you experience abdominal pain, nausea, or vomiting. These may be signs of inflammation of your gallbladder or pancreas. Your doctor will also do studies to test for gallstones.

    Trilipix can cause serious muscle conditions that may lead to kidney damage. Your risk can increase if you are also taking statins. Tell your doctor immediately if you experience unexplained muscle pain, weakness, or tenderness, especially if you also have a fever or general body discomfort.

    Trilipix can cause pancreatitis (inflammation of the pancreas), severe allergic reactions, blood abnormalities, and clotting problems.

  • Who should not take Trilipix?

    Do not take Trilipix if you are allergic to it or any of its ingredients; or if you have liver, gallbladder, or severe kidney problems; if you are receiving dialysis; or are breastfeeding.

  • What should I tell my doctor before I take the first dose of Trilipix?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Trilipix. Also, talk to your doctor about your complete medical history, especially if you have liver, kidney, or gallbladder problems; hypothyroidism (an underactive thyroid gland); diabetes; blood disorders; muscle pain or disease; or pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    High Cholesterol Levels or a Combination of High Cholesterol and High Triglycerides

    Adults: The recommended dose is 135 milligrams (mg) a day.

    High Triglyceride Levels

    Adults: The recommended starting dose is 45-135 mg a day.

    If you have kidney problems, your doctor will adjust your dose appropriately.

  • How should I take Trilipix?

    Take Trilipix exactly as prescribed by your doctor.

    Swallow Trilipix capsules whole. Do not break, crush, dissolve, or chew the capsules before swallowing.

    If you are taking Trilipix with another type of cholesterol-lowering medicine called a bile acid sequestrant (such as colestipol or cholestyramine), take Trilipix at least 1 hour before or 4-6 hours after you take the other medicine.

  • What should I avoid while taking Trilipix?

    Do not breastfeed while you are taking Trilipix.

  • What are possible food and drug interactions associated with Trilipix?

    If Trilipix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Trilipix with the following: bile acid sequestrants, blood thinners, cyclosporine, or statins.

  • What are the possible side effects of Trilipix?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, back pain, constipation, diarrhea, headache, indigestion, liver damage, muscle pain, nausea, respiratory problems

  • Can I receive Trilipix if I am pregnant or breastfeeding?

    The effects of Trilipix during pregnancy are unknown. Do not breastfeed while you are taking Trilipix. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Trilipix?

    If you miss a dose of Trilipix, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Trilipix?

    Store at room temperature. Protect from moisture.