Truvada

Generic Name: Tenofovir Disoproxil

  • What is Truvada?

    Truvada is a combination medicine used to treat HIV (human immunodeficiency virus) infection (AIDS) with other anti-HIV medications. Truvada contains two medications, emtricitabine and tenofovir disoproxil fumarate. Both of these are types of HIV medications called nucleoside analogue reverse transcriptase inhibitors (NRTIs). Truvada works by lowering the amount of HIV in your blood.

  • What is the most important information I should know about Truvada?

    You must take Truvada with other HIV medications. Always stay on continuous HIV therapy to control your HIV infection and decrease HIV-related illnesses. Though Truvada can slow the progress of HIV, it is not a cure. Also, Truvada does not lower your chance of passing HIV/AIDS to others through sexual contact, sharing needles, or being exposed to your blood. You may continue to develop infections and other complications associated with HIV.

    Truvada can cause a rare but serious condition called lactic acidosis (a build-up of an acid in the blood). Tell your doctor immediately if you feel very weak or tired; have unusual muscle pain; trouble breathing, or stomach pain with nausea and vomiting; feel cold, especially in your arms and legs; feel dizzy or lightheaded; or have a fast or irregular heartbeat.

    Truvada can cause serious liver problems with liver enlargement and fat in the liver. Tell your doctor immediately if you experience yellowing of your skin or whites of your eyes, dark urine, light-colored stools, loss of appetite, nausea, or lower abdominal pain.

    You have a higher chance of getting lactic acidosis or liver problems if you are a woman, are very overweight, or if you have been taking Truvada or similar products for a long time.

    If you have hepatitis B virus (HBV) and stop taking Truvada, your HBV can worsen.

  • Who should not take Truvada?

    Do not take Truvada if you are allergic to it or any of its ingredients.

    Do not take Truvada if you are already taking other HIV medications containing the same or similar active ingredients (such as Atripla, Combivir, Emtriva, Epivir or Epivir-HBV, Epzicom, Trizivir, or Viread) or Hepsera.

  • What should I tell my doctor before I take the first dose of Truvada?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Truvada. Also, talk to your doctor about your complete medical history, especially if you have liver problems, including HBV; bone or kidney problems; or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥12 years: The recommended dose is 1 tablet once a day.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Truvada?

    Take Truvada exactly as prescribed by your doctor. You can take Truvada with or without a meal. Take Truvada at the same time each day.

    When your Truvada supply starts to run low, get more from your doctor or pharmacy. It is important that you do not run out of Truvada. If you stop the medicine for even a short time, the amount of HIV in your body can increase or it can become resistant to the effects of Truvada.

  • What should I avoid while taking Truvada?

    Do not become pregnant or breastfeed while you are taking Truvada. If you do become pregnant, contact your doctor immediately.

    Do not reuse or share needles or other injection equipment. Also, do not share personal items that can have blood or bodily fluids on them (such as toothbrushes or razor blades).

    Do not have unprotected sex.

  • What are possible food and drug interactions associated with Truvada?

    If Truvada is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Truvada with the following: certain HIV medications (such as atazanavir, didanosine, lopinavir/ritonavir), Hepsera, medications affecting your kidney function (such as acyclovir, adefovir dipivoxil, cidofovir, ganciclovir, valacyclovir, or valganciclovir), or other HIV medications containing the same or similar active ingredients.

  • What are the possible side effects of Truvada?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abnormal dreams, depression, diarrhea, dizziness, headache, kidney problems, nausea, rash, sleeping problems, thinning bones, tiredness, vomiting

  • Can I receive Truvada if I am pregnant or breastfeeding?

    The effects of Truvada during pregnancy and breastfeeding are unknown. It is recommended that you do not breastfeed your baby if you are infected with HIV. This is because your baby could become infected with HIV through your breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Truvada?

    If you miss a dose of Truvada, take it as soon as you remember that day. Do not take more than 1 dose of Truvada in a day. Do not take 2 doses at the same time.

  • How should I store Truvada?

    Store at room temperature.