Generic Name: Hydrocodone polistirex and chlorpheniramine polistirex

  • What is Tussionex?

    Tussionex Extended-Release Suspension is a cough suppressant/antihistamine combination used to relieve coughs and the upper respiratory symptoms of colds and allergies.
  • What is the most important information I should know about Tussionex?

    This medication can cause considerable drowsiness and make you less alert. You should not drive or operate machinery or participate in any activity that requires full mental alertness until you know how you react to Tussionex.

    Tussionex contains a mild narcotic that can cause dependence and tolerance when the drug is used for several weeks. However, it is unlikely that dependence will develop when Tussionex is used for the short-term treatment of a cough.

  • Who should not take Tussionex?

    Do not take Tussionex if you are sensitive to or have ever had an allergic reaction to hydrocodone or chlorpheniramine. Make sure your doctor is aware of any drug reactions you have experienced.

    Tussionex is contraindicated in children less than 6 years of age due to increased risk of fatal respiratory depression.

  • What should I tell my doctor before I take the first dose of Tussionex?

    Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tussionex. Also, talk to your doctor about your complete medical history, especially if you have an enlarged prostate gland, an eye condition known as narrow-angle glaucoma, an intestinal disorder, or an underactive thyroid gland. Make sure to let your doctor know if you have asthma, liver or kidney disease, lung disease or a breathing disorder, urinary difficulties, Addison's disease (a disorder of the adrenal glands), or if you have recently suffered a head injury.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dose is 1 teaspoonful (5 milliliters) every 12 hours. Do not take more than 2 teaspoonfuls in 24 hours.

    Children 6 to 12 years old: The usual dose is one-half teaspoonful every 12 hours. Do not take more than 1 teaspoonful in 24 hours.

    Tussionex is not recommended for children under 6 years old.

  • How should I take Tussionex?

    Tussionex should be taken exactly as prescribed. Do not dilute it with other liquids or mix it with other drugs. Shake well before using. Use an appropriate measuring device; a household teaspoon may not be an accurate dosage measurement.
  • What should I avoid while taking Tussionex?

    Tussionex may increase the effects of alcohol. Do not drink alcohol while taking Tussionex.
  • What are possible food and drug interactions associated with Tussionex?

    If Tussionex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tussionex with the following: alcohol, antihistamines (such as diphenhydramine), antispasmodic medications (such as dicyclomide and benztropine), major tranquilizers (such as chlorpromazine and prochlorpromazine), MAO inhibitor drugs (antidepressants such as phenelzine and tranylcypromine), medications for anxiety (such as alprazolam and diazepam), medications for depression (such as amitriptyline and fluoxetine), or narcotics (such as acetaminophen/oxycodone and meperidine).
  • What are the possible side effects of Tussionex?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: anxiety, constipation, decreased mental and physical performance, difficulty breathing, difficulty urinating, dizziness, drowsiness, dry throat, emotional dependence, exaggerated feeling of depression, extreme calm, exaggerated sense of well-being, fear, itching, mental clouding, mood changes, nausea, rash, restlessness, sluggishness, tightness in chest, vomiting

  • Can I receive Tussionex if I am pregnant or breastfeeding?

    The effects of Tussionex during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
  • What should I do if I miss a dose of Tussionex?

    If you take Tussionex on a regular schedule, take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and go back to your regular schedule. Do not take 2 doses at once.
  • How should I store Tussionex?

    Store at room temperature in a tightly closed container.