Generic Name: Telmisartan

  • What is this medication and its most common uses?

    Twynsta is a medicine used alone or in combination with other medicines to treat high blood pressure. Twynsta contains two medicines that work in two different ways to reduce your blood pressure: amlodipine and telmisartan.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Twynsta works by blocking a chemical in your body that causes blood vessels to narrow. By blocking this chemical, Twynsta relaxes and widens your blood vessels, allowing your blood to flow through with less resistance. This helps to lower your blood pressure.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: By lowering your blood pressure, Twynsta may lower your risk of a stroke or a heart attack.

    When: Twynsta may start lowering your blood pressure within 2 weeks. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider may also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Twynsta can harm your unborn baby. Talk to your healthcare provider about other ways to lower your blood pressure if you plan to become pregnant. Tell your healthcare provider right away if you become pregnant while taking Twynsta.

    More common side effects may include: swelling in your hands, ankles, or feet; dizziness; back pain.

    Less common side effects may include:

    Low blood pressure with symptoms such as fainting or dizziness. Low blood pressure is most likely to happen if you also take water pills, are on a low-salt diet, get dialysis treatment, have heart problems, or get sick with vomiting or diarrhea.

    Worsening kidney problems with symptoms such as swelling in your feet, ankles, or hands; or unexplained weight gain.

    Possible increased chest pain or risk of a heart attack.

    High potassium in the blood.

  • Who should not take this medication?

    Do not take Twynsta if you are allergic to it or any of its ingredients.

    Do not take Twynsta if you have diabetes and are taking another blood pressure medicine called aliskiren.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Twynsta. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes; kidney, liver, or heart problems; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The usual starting dose is 40/5 (40 milligrams [mg] of telmisartan and 5 mg of amlodipine) once a day. Your healthcare provider will increase your dose as needed, until the desired effect is achieved.

    If you have liver impairment or are elderly, your healthcare provider may adjust your dose appropriately.

  • How should I take this medication?

    Take Twynsta exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Twynsta without first talking to your healthcare provider.

    Take Twynsta at the same time every day, either with or without food.

  • What should I avoid while taking this medication?

    Do not become pregnant while taking this medication.

    Do not take potassium supplements or salt substitutes that contain potassium without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If Twynsta is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Twynsta with the following: certain diuretics (water pills) (such as spironolactone or triamterene), digoxin, diltiazem, itraconazole, ketoconazole, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen), potassium-containing supplements or salt substitutes, ramipril, ritonavir, or simvastatin.

  • May I receive this medication if I am pregnant or breastfeeding?

    Do not take Twynsta if you are pregnant or breastfeeding. Twynsta can harm your unborn baby. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Twynsta, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from light and moisture.

    Do not remove Twynsta tablets from blisters until right before you take them.

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