Generic Name: Tigecycline

  • What is Tygacil?

    Tygacil is an antibiotic used to treat certain bacterial infections of the skin, abdomen, or lower respiratory (lung) tract. It may also be used to treat other bacterial infections, as determined by your doctor. Tygacil is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Tygacil?

    Tygacil can cause allergic reactions that may result in death if not immediately treated. If you are allergic to similar antibiotics (such as doxycycline or tetracycline), it is possible for you to have an allergic reaction to this medication. Tell your doctor immediately if you receive Tygacil and you develop a rash, swelling, or difficulty breathing.

    Tygacil can cause liver impairment or pancreatitis (inflammation of the pancreas). Your doctor will monitor you for evidence of worsening liver function or pancreatitis.

    Tygacil can cause permanent discoloration (yellow-gray-brown) of your child's teeth if it is taken during early tooth development.

    Tygacil can cause diarrhea or colitis (inflammation of the colon). This can occur a couple of months after receiving the last dose of Tygacil. Tell your doctor immediately if you have diarrhea or colitis.

  • Who should not take Tygacil?

    Your doctor will not administer Tygacil to you if you are allergic to it or any of its ingredients.

    Your doctor will not administer Tygacil to you to treat viral infections, such as the common cold.

  • What should I tell my doctor before I take the first dose of Tygacil?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tygacil. Also, talk to your doctor about your complete medical history, especially if you have allergies, liver disease, intestinal disease, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults ≥18 years: The recommended starting dose is 100 milligrams (mg), followed by 50 mg every 12 hours. Your doctor will determine the duration of treatment based on the type and severity of your infection.

    If you have severe liver impairment, your doctor will adjust your dose appropriately.

  • How should I take Tygacil?

    Your doctor will administer Tygacil for you in a hospital setting.

  • What should I avoid while taking Tygacil?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Tygacil?

    If Tygacil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior treatment with Tygacil: birth control pills or blood thinners (such as warfarin).

  • What are the possible side effects of Tygacil?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, abnormal healing, allergic reactions, diarrhea, headache, liver problems, nausea, pancreatitis, vomiting

  • Can I receive Tygacil if I am pregnant or breastfeeding?

    The effects of Tygacil during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Tygacil?

    Tygacil should be given under special circumstances determined by your doctor.

  • How should I store Tygacil?

    Your doctor will store this medication for you.