Tyvaso

Generic Name: Treprostinil

  • What is this medication and its most common uses?

    Tyvaso is a medicine used to improve exercise ability in people with pulmonary arterial hypertension (PAH) (high blood pressure in the arteries of your lungs). Tyvaso is available as a solution for inhalation.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Over time, the arteries in the lungs of people with PAH become narrow. This narrowing decreases the blood flow from the heart to the lungs. Tyvaso mimics the action of a substance that is naturally produced by your body to help keep arteries open and make platelets (a type of blood cells that form clots to help stop bleeding) less sticky.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Tyvaso has been shown to improve exercise ability, such as the distance you are able to walk.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is very important to keep using Tyvaso as prescribed to keep your condition under control.

    How do I know it is working?

    You may notice an improvement in your exercise ability once you begin using Tyvaso. This is a good indicator that your medication is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: cough, headache, sore throat, nausea, flushing (warm, hot, burning feeling to your face), fainting.

    Less common side effects may include:

    Increased risk of bleeding, especially in people who take blood thinners (such as warfarin).

    Decreased blood pressure, especially in people who already have low blood pressure.

  • Who should not take this medication?

    Do not use Tyvaso if you are allergic to it or any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tyvaso. Also, talk to your healthcare provider about your complete medical history, especially if you have lung disease (such as asthma or chronic obstructive pulmonary disease), a lung infection, kidney or liver problems, low blood pressure, or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended starting dose is 3 inhalations per treatment session, 4 times a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

  • How should I take this medication?

    Use Tyvaso exactly as prescribed by your healthcare provider. Do not change your dose or stop using Tyvaso without first talking to your healthcare provider.

    Tyvaso is breathed in (inhaled) through your mouth into your lungs. Tyvaso should only be used with the Tyvaso Inhalation System.

    Tyvaso is used in 4 treatment sessions every day, during waking hours. The treatment sessions should be about 4 hours apart.

    Once the foil pouch is opened, use Tyvaso ampules within 7 days. After you open a Tyvaso ampule and put it into the medicine cup in the Tyvaso Inhalation System, it can be kept in the medicine cup for no more than 1 day (24 hours). Any remaining solution left in the medicine cup at the end of the day should be thrown away.

    Please review the instructions that came with your prescription on how to properly prepare and use your Tyvaso Inhalation System.

  • What should I avoid while taking this medication?

    Do not get Tyvaso solution into your eyes or onto your skin. If it does, rinse your eyes or skin right away with water. Do not mix Tyvaso with other medications in the Tyvaso Inhalation System.

  • What are the possible food and drug interactions associated with this medication?

    If Tyvaso is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Tyvaso with the following: blood pressure/heart medications, blood thinners, gemfibrozil, rifampin, or water pills (such as furosemide).

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Tyvaso during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Tyvaso, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not inhale two doses at once.

  • How should I store this medication?

    Store the unopened foil pouch at room temperature.