Generic Name: Tramadol

  • What is Ultram?

    Ultram is an opioid analgesic (pain killer) that is used in the management of moderate to moderately severe pain in patients ≥17 years.

  • What is the most important information I should know about Ultram?

    Ultram has been shown to cause seizures, especially in patients taking certain antidepressants (selective serotonin reuptake inhibitors and tricyclic antidepressants), some opioids, and MAO inhibitors. There is a greater risk of seizures if you have a history of seizures, have drug/alcohol withdrawal, or a nervous system infection.

    Ultram may cause dependence. You should not use it if you have previously been addicted to an opioid.

    The development of a potentially life-threatening adverse event known as serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) may develop when using Ultram. This may especially be true for patients who are taking certain other medications. Contact your doctor immediately if you experience any signs of serotonin syndrome, such as mental-status changes, increase in heart rate, fever, incoordination, and/or stomach problems.

  • Who should not take Ultram?

    Do not take Ultram if you are allergic to tramadol or any of its other ingredients. Also, do not take this drug if you are currently using alcohol, analgesics, narcotics, opioids, or other antidepressants.

  • What should I tell my doctor before I take the first dose of Ultram?

    Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ultram. Also, talk to your doctor about your complete medical history, especially if you have a history of drug/alcohol abuse, depression, liver or kidney problems, head injury, or seizures.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults ≥17 years: The usual starting dose is 25 milligrams (mg) daily. Your doctor will increase your dose over a course of several days as needed. Do not exceed 400 mg a day.

  • How should I take Ultram?

    Take Ultram exactly as prescribed by your doctor. Do not adjust the dose or use Ultram for longer than recommended by your doctor. Overdosing may result in depression, seizures, or even death.

  • What should I avoid while taking Ultram?

    Avoid using drugs/alcohol or antidepressants without consulting your doctor first. Using these products may cause seizures.

    Avoid operating a car or heavy machinery while taking Ultram, as it can impair your physical and mental awareness.

  • What are possible food and drug interactions associated with Ultram?

    If Ultram is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Ultram with the following: alcohol, amitriptyline, carbamazepine, CNS depressants, digoxin, erythromycin, ketoconazole, linezolid, MAO inhibitors, opioids, quinidine, SSRIs, St. John's wort, tricyclic antidepressants, triptans, and warfarin.

  • What are the possible side effects of Ultram?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, diarrhea, dizziness, dry mouth, headache, itchiness, nausea, sleeplessness, sweating, upset stomach, vomiting, weakness

  • Can I receive Ultram if I am pregnant or breastfeeding?

    The effects of Ultram during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Ultram?

    Ultram is taken on an as-needed basis when you are experiencing pain. If you miss a dose and have pain, take the missed dose. Do not take two doses at once.

  • How should I store Ultram?

    Store at room temperature.

Meet the Pharmacists

I'm Kristen Dore, PharmD. Welcome to PDR Health!

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