Generic Name: Doxycycline

  • What is Vibramycin?

    Vibramycin is an antibiotic used to treat a wide variety of bacterial infections, including Rocky Mountain spotted fever, respiratory tract and urinary tract infections, some gonococcal infections, Chlamydia, and inhalational anthrax. It is also used with other medicines to treat infections of the intestines and severe acne. Vibramycin may also be taken for the prevention of malaria on foreign trips of <4 months' duration.

  • What is the most important information I should know about Vibramycin?

    Like all antibiotics, Vibramycin is only effective against bacterial infections. It will not treat viral infections such as the common cold or flu.

    Children <8 years and women in the last half of pregnancy should not take this medication. It may cause developing teeth to become permanently discolored. Another tooth condition called enamel hypoplasia has also been reported with the use of this drug. Children <8 years may be given this drug for post-exposure inhalational anthrax.

    As with other antibiotics, treatment with Vibramycin may result in a growth of bacteria that do not respond to this medication and can cause a secondary infection.

    Vibramycin may make your skin more sensitive to light. Use adequate sun protection while taking Vibramycin.

    Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea, although rare, may occur. Contact your doctor right away if you experience stomach pain or cramps, severe diarrhea, or bloody stools. Do not treat the diarrhea without first checking with your doctor.

  • Who should not take Vibramycin?

    Do not use Vibramycin if you have a history of allergic reactions to any tetracyclines. Make sure your doctor is aware of any drug reactions that you have experienced.

  • What should I tell my doctor before I take the first dose of Vibramycin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Vibramycin. Also talk to your doctor about your complete medical history, especially if you have lupus, liver or kidney disease, if you are pregnant or planning to become pregnant, or if you are allergic to sulfites.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dose of oral Vibramycin is 200 milligrams (mg) on the first day of treatment (100 mg every 12 hours) followed by a maintenance dose of 100 mg per day. The maintenance dose may be taken as a single dose or as 50 mg every 12 hours.

    Your doctor may prescribe 100 mg every 12 hours for severe infections such as chronic urinary tract infection.

    Children 8 years and older: The recommended dosage schedule for those weighing 100 pounds or less is 2 mg per pound of body weight, divided into 2 doses on the first day of treatment, followed by 1 mg per pound of body weight given as a single daily dose or divided into 2 doses on subsequent days. For more severe infections, up to 2 mg per pound of body weight may be used. For children over 100 pounds, the usual adult dose should be used.

    Gonorrhea (Uncomplicated)

    Adults: The usual dose is 100 milligrams (mg) by mouth, twice a day for 7 days. An alternate, single-day treatment is 300 mg, followed in 1 hour by a second 300-mg dose.

    Inhalational Anthrax

    Adults: The usual dose is 100 mg twice a day for 60 days.

    Children <100 pounds: The usual dose is 1 mg per pound of body weight twice daily for 60 days.

    Children >100 pounds: The usual adult dose should be used.

    Malaria (Prevention)

    Adults: The usual dose is 100 mg a day. Treatment should begin 1 to 2 days before travel to the area where malaria is found, then continue daily during travel in the area and 4 weeks after leaving.

    Children: The recommended dose is 2 mg per 2.2 pounds of body weight up to 100 mg. Treatment should begin 1 to 2 days before travel to the area where malaria is found, then continue daily during travel in the area and 4 weeks after leaving.


    Adults: The usual dose is 100 mg twice a day, for 2 to 4 weeks, depending upon how long you've had the infection.

  • How should I take Vibramycin?

    Take Vibramycin with a full glass of water or other liquid to avoid irritating your throat or stomach. Vibramycin can be taken with or without food. However, if the medicine upsets your stomach, take it with a glass of milk or after you have eaten.

    If you are taking an oral suspension form of Vibramycin, shake the bottle well before using.

    It's important to take the full dosage schedule of Vibramycin, even if you're feeling better in a few days. Not completing the full dosage schedule may decrease the drug's effectiveness and increase the chances that the bacteria may become resistant to Vibramycin and similar antibiotics. If this happens, Vibramycin and similar antibiotics may not work in the future.

  • What should I avoid while taking Vibramycin?

    Avoid excessive exposure to sunlight or sunlamps.

  • What are possible food and drug interactions associated with Vibramycin?

    If Vibramycin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Vibramycin with the following: antacids containing aluminum, calcium, or magnesium, and iron-containing preparations, barbiturates, bismuth subsalicylate, blood-thinning medications, carbamazepine, oral contraceptives, penicillin, methoxyflurane, and phenytoin.

  • What are the possible side effects of Vibramycin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, nausea, vomiting, loss of appetite, rash, difficulty swallowing, discolored teeth in infants and children (more common during long-term use of tetracycline), inflammation of the tongue, skin sensitivity to light

  • Can I receive Vibramycin if I am pregnant or breastfeeding?

    Vibramycin should not be used during pregnancy. Vibramycin can damage developing teeth during the last half of pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Tetracyclines such as Vibramycin appear in breast milk and can affect a nursing infant. Consult your doctor before breastfeeding.

  • What should I do if I miss a dose of Vibramycin?

    If you miss a dose of Vibramycin, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.

  • How should I store Vibramycin?

    Store at room temperature. Protect from light and excessive heat.

Starting a GERD or Ulcer Drug?

Our nine-week newsletter series, written by a pharmacist, will help you learn about your medication.
Sign Up

Meet the Pharmacists

I'm Kristen Dore, PharmD. Welcome to PDR Health!

Check out my latest blog post on heartburn medication

Vibramycin Related Drugs

Vibramycin Related Conditions