Vitrasert

Generic Name: Ganciclovir

  • What is Vitrasert?

    Vitrasert is an eye implant used to treat cytomegalovirus (CMV) retinitis (eye disease that involves damage to the layer of tissue in the back of the eye called the retina) in patients with acquired immunodeficiency syndrome (AIDS).

  • What is the most important information I should know about Vitrasert?

    The surgical placement of Vitrasert implant into your eye can cause eye infections or inflammation, vitreous (a thick, transparent substance that fills the center of the eye) loss, vitreous bleeding, cataracts (clouding of the eye's lens), retinal detachment, inflammation of the middle layer of the eye, inflammation of the internal coats of the eye, or decrease in your visual clarity.

    Following the implant surgery, you may experience an immediate and temporary decrease in your visual clarity that lasts for 2-4 weeks after your surgery.

    Vitrasert is not a cure for CMV retinitis; you may continue to experience worsening of your retinitis even with Vitrasert implant. Do not miss your follow-up eye examinations with your doctor after your surgery.

    Vitrasert only treats eyes in which it has been implanted. Your doctor will check you for other CMV infections in other parts of your body and outside your eyes.

  • Who should not take Vitrasert?

    Your doctor will not implant Vitrasert into your eye(s) if you are allergic to ganciclovir or acyclovir, or have a condition that does not allow you to have eye surgery (such as an infection or certain blood disorders).

  • What should I tell my doctor before I take the first dose of Vitrasert?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Vitrasert. Also, talk to your doctor about your complete medical history, especially if you have a history of blood disorders, cataracts, fertility problems, infections; or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥9 years: Your doctor will surgically place Vitrasert implant into your or your child's eye.

  • How should I take Vitrasert?

    Your doctor will surgically place Vitrasert implant for you.

  • What should I avoid while taking Vitrasert?

    Do not miss your follow-up appointments with your eye doctor following the implant.

  • What are possible food and drug interactions associated with Vitrasert?

    No significant interactions have been reported with Vitrasert at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Vitrasert?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: blood in the front chamber of your eye, cataracts, eye bleeding, increased eye pressure, inflammation of the middle layer of your eye, loss of visual clarity, nerve changes in your eye, retinal detachment

  • Can I receive Vitrasert if I am pregnant or breastfeeding?

    The effects of Vitrasert during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Vitrasert?

    Vitrasert implant should be used under special circumstances determined by your doctor.

  • How should I store Vitrasert?

    Your doctor will store this medication for you.