What is Vivelle-Dot?Vivelle-Dot is a transdermal patch (applied to your skin) that contains the estrogen hormone, estradiol. It is used to treat moderate to severe symptoms of menopause, such as hot flashes or severe dryness, itching, and burning in or around your vagina. Also, Vivelle-Dot is used to treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally, and to reduce your chances of getting postmenopausal osteoporosis (thin, weak bones).
What is the most important information I should know about Vivelle-Dot?Estrogens increase your risk of developing cancer of the uterus. Tell your doctor immediately if you experience any unusual vaginal bleeding while you are using Vivelle-Dot.
Do not use Vivelle-Dot to prevent heart disease, heart attacks, strokes, or dementia. Using Vivelle-Dot can increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.
Vivelle-Dot can also increase your risk of dementia, gallbladder disease, ovarian cancer, visual abnormalities, high blood pressure, pancreatitis (inflammation of your pancreas), or thyroid problems. Talk regularly with your doctor about whether you still need treatment with Vivelle-Dot.
You can lower your changes of serious side effects with Vivelle-Dot by having a breast exam and mammogram (breast x-ray) every year, unless directed by your doctor to have it more often. See your doctor immediately if you get vaginal bleeding while you are using Vivelle-Dot. Also, ask your doctor for ways to lower your chances of getting heart disease, especially if you have high blood pressure, high cholesterol, or diabetes, if you are overweight, or if you use tobacco.
Who should not take Vivelle-Dot?Do not use Vivelle-Dot if you are allergic to it or any of its ingredients, or if you are pregnant or think you may be pregnant.
Do not use Vivelle-Dot if you have a history of stroke or heart attack, blood clots, liver problems, unusual vaginal bleeding, or certain cancers, including cancer of your breast or uterus.
What should I tell my doctor before I take the first dose of Vivelle-Dot?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Vivelle-Dot. Also, talk to your doctor about your complete medical history, especially if you are pregnant or breastfeeding, or have any unusual vaginal bleeding, asthma, seizures, diabetes, migraine headaches, endometriosis (a common gynecological disorder that may result in sores and pain), lupus (disease that affects the immune system), high blood calcium levels, or problems with your heart, liver, thyroid, or kidneys. Also, tell your doctor if you are going to have surgery or will be on bedrest.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Apply 1 patch to your skin, and replace the patch twice a week.
How should I take Vivelle-Dot?Use Vivelle-Dot exactly as prescribed by your doctor. Talk to your doctor regularly (every 3-6 months) about whether you still need treatment with Vivelle-Dot.
Each patch is individually sealed in a protective pouch. Tear open at the tear notch (do not use scissors). Remove the patch. Holding the patch with the rigid protective liner facing you, remove half of the liner, which covers the sticky surface of the patch. Using the other half of the rigid protective liner as a handle, apply the sticky side of the patch to the selected area of your abdomen.
When changing your patch, apply your new patch to a different area of your body. Do not apply a new patch to that same area for at least 1 week.
Please review the instructions that came with your prescription on how to properly use Vivelle-Dot.
What should I avoid while taking Vivelle-Dot?Do not apply Vivelle-Dot onto your breasts; waistline; or onto areas of your skin that are oily, damaged, or irritated.
Do not touch the sticky side of the patch with your fingers.
Grapefruit juice can increase your risk of side effects with Vivelle-Dot. Talk to your doctor before including grapefruit or grapefruit juice in your diet while you are using Vivelle-Dot.
What are possible food and drug interactions associated with Vivelle-Dot?If Vivelle-Dot is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Vivelle-Dot with the following: carbamazepine, clarithromycin, erythromycin, grapefruit juice, itraconazole, ketoconazole, phenobarbital, rifampin, ritonavir, or St. John's wort.
What are the possible side effects of Vivelle-Dot?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, application-site redness, back pain, bloating, breast pain, constipation, dizziness, fluid retention, hair loss, headache, indigestion, infection, irregular vaginal bleeding or spotting, joint pain or inflammation, muscle pain, nausea, pain, rash, vaginal yeast infection, vomiting
If you experience symptoms of breast lumps, changes in your speech, changes in your vision, chest pain, dizziness and faintness, pain in your legs, severe headaches, shortness of breath, unusual vaginal bleeding, or vomiting, contact your doctor immediately.
Can I receive Vivelle-Dot if I am pregnant or breastfeeding?Do not use Vivelle-Dot if you are pregnant. The hormone in Vivelle-Dot can be found in your breast milk if you use it while you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Vivelle-Dot?Vivelle-Dot should be used under special circumstances determined by your doctor. If you miss your scheduled dose, contact your doctor or pharmacist for advice.
How should I store Vivelle-Dot?Store at room temperature. Do not store the patch outside of the pouch.