Generic Name: Antihemophilic Factor (Recombinant)

  • What is Xyntha?

    Xyntha is an injectable medicine used to help control and prevent bleeding in people with hemophilia A.
  • What is the most important information I should know about Xyntha?

    Xyntha is not to be used treat von Willebrand's disease.
  • Who should not take Xyntha?

    Do not use Xyntha if you have a known hypersensitivity to any of its ingredients.
  • What should I tell my doctor before I take the first dose of Xyntha?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Xyntha. Also talk to your doctor about your complete medical history, especially if you are pregnant or planning to become pregnant or if you are breastfeeding.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Dosage and duration of treatment vary depending on the severity of the disease, the location and extent of bleeding, and the patient's clinical condition.

  • How should I take Xyntha?

    Xyntha has to be reconstituted first using the diluent. Gently swirl the content of the vials until the powder is completely dissolved. The solution should be clear to slightly opalescent and colorless. Next, draw the solution into the syringe. Attach the syringe to the luer end of the provided infusion set tubing. Apply a tourniquet and prepare the injection site by wiping the skin with alcohol swab. Insert the butterfly needle of the infusion set tubing into your vein. Remove the tourniquet and infuse the reconstituted Xyntha over several minutes. After infusion, remove the infusion set and discard.
  • What should I avoid while taking Xyntha?

    Do not use Xyntha more than 3 hrs after it has been reconstituted. Do not use Xyntha after the expiration date.
  • What are possible food and drug interactions associated with Xyntha?

    If Xyntha is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Xyntha with other medications.
  • What are the possible side effects of Xyntha?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, nausea, vomiting, headache, fever.

    Signs of severe allergic reactions may include hives, difficulty breathing, and swelling of the throat. If any of these events occur, seek immediate medical attention.

  • Can I receive Xyntha if I am pregnant or breastfeeding?

    Xyntha is to be avoided during pregnancy and breastfeeding.
  • What should I do if I miss a dose of Xyntha?

    If you miss a dose, contact your doctor for instructions.
  • How should I store Xyntha?

    Store Xyntha at 2-8°C (36-46°F) in the refrigerator. Xyntha can last at room temperature for up to 3 months. Store the diluent syringe at 2-25°C or 36-77°F. After reconstituting, Xyntha can last at room temperature for up to 3 hours.