Generic Name: Omeprazole and sodium bicarbonate

  • What is Zegerid?

    Zegerid is used to treat intestinal ulcers (duodenal ulcers), stomach ulcers (gastric ulcers), gastroesophageal reflux disease (GERD), and erosive esophagitis.
  • What is the most important information I should know about Zegerid?

    Both the capsule and oral suspension forms of Zegerid can be taken with water and on an empty stomach. Do not substitute any other food or liquid in the place of water. Do not open the capsule and sprinkle the contents into food.
  • Who should not take Zegerid?

    Do not take Zegerid if you are allergic to any of its ingredients.
  • What should I tell my doctor before I take the first dose of Zegerid?

    Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zegerid. Also, talk to your doctor about your complete medical history, especially if you are on a sodium-restricted diet.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Benign Gastric Ulcer

    Adults: The recommended dosage is 40 milligrams (mg) once daily for 4-8 weeks.

    Erosive Esophagitis

    Adults: The recommended dosage is 20 mg once daily for 4-8 weeks. To maintain healing of erosive esophagitis, the daily dose is 20 mg for as long as the doctor prescribes Zegerid.

    Short-Term Treatment of Active Duodenal Ulcer

    Adults: The recommended dosage is 20 mg once daily for 4 weeks.

    Symptomatic GERD

    Adults: The recommended dosage is 20 mg once daily for up to 4 weeks.

    Upper Gastrointestinal Bleeding

    Adults: The recommended oral suspension dosage begins at 40 mg, followed by 40 mg 6-8 hours later and 40 mg daily for 14 days.

    Zegerid has not been studied in patients under the age of 18.

  • How should I take Zegerid?

    Zegerid capsules should be swallowed whole with water on an empty stomach 1 hour before a meal. Do not use any other liquid than water. Do not open the capsule and sprinkle on food.

    Zegerid oral suspension should be emptied into a small cup with 1-2 tablespoons of water. Do not use any other liquid than water. Stir well and drink. Refill the cup with water and drink the remainder.

  • What should I avoid while taking Zegerid?

    Avoid taking food simultaneously with Zegerid. Zegerid should be taken on an empty stomach at least 1 hour before a meal. Both 20 mg and 40 mg of Zegerid contain the same amount of one ingredient; therefore, do not substitute two 20-mg capsules or oral suspension packets for a 40-mg dose.
  • What are possible food and drug interactions associated with Zegerid?

    If Zegerid is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zegerid with the following: atazanavir, diazepam, other proton pump inhibitors, phenytoin, tacrolimus, or warfarin.
  • What are the possible side effects of Zegerid?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: aches, back pain, constipation, cough, diarrhea, dizziness, headache, nausea, rash, upper respiratory infection, vomiting

  • Can I receive Zegerid if I am pregnant or breastfeeding?

    The effects of Zegerid during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding. Zegerid is passed into breast milk.
  • What should I do if I miss a dose of Zegerid?

    If you miss a dose of Zegerid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
  • How should I store Zegerid?

    Store both the capsules and oral suspension at room temperature.