Zenpep

Generic Name: Pancrelipase

  • What is Zenpep?

    Zenpep is a medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis or other conditions. Zenpep may help your body use fats, proteins, and sugars from food. Zenpep contains a mixture of digestive enzymes, including lipases, proteases, and amylases from pig pancreas.

  • What is the most important information I should know about Zenpep?

    Zenpep can increase your chance of having a rare bowel disorder with scarring or thickening of your bowel wall. This condition is serious and may require surgery. The risk of having this condition may be reduced by following the dosing instructions that your doctor gave you. Tell your doctor immediately if you experience unusual or severe stomach area pain, bloating, trouble passing stool, nausea, vomiting, or diarrhea.

    Crushing, chewing, or holding the Zenpep capsules in your mouth can cause irritation in your mouth or change the way Zenpep works in your body.

    Zenpep can cause serious side effects, such as an increase in your blood uric acid levels, which may cause worsening of gout (swollen, painful joints). Tell your doctor if you experience any of these symptoms.

    Zenpep is made from the pancreas of pork (pigs). These pigs may carry viruses that can cause viral infections.

    Zenpep can cause allergic reactions, including trouble breathing, skin rash, or swollen lips. Tell your doctor immediately if you experience any of these symptoms.

  • Who should not take Zenpep?

    Do not take Zenpep if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Zenpep?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zenpep. Also, talk to your doctor about your complete medical history, especially if you have a history of abnormal sugar levels, are allergic to pork products, have trouble swallowing capsules, have a history of blockage of your intestines, scarring or thickening of your bowel wall, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children: The doctor will prescribe the appropriate dose for you or your child based on the age, weight, and condition. Your doctor may change your dose based on the amount of fatty foods eaten.

  • How should I take Zenpep?

    Take Zenpep exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor.

    Do not switch Zenpep with any other pancreatic enzyme product without first talking to your doctor.

    Always take Zenpep with a meal or snack and enough liquid to swallow it completely. If you eat a lot of meals or snacks in a day, be careful not to go over your total daily dose.

    Infants (Children up to 12 Months)

    Give Zenpep right before each feeding of formula or breast milk.

    Open the capsules and sprinkle the contents directly into your infant's mouth or mix the contents in a small amount of room temperature acidic soft food, such as applesauce, pureed bananas, or pears. These foods should be the kind found in baby food jars that you buy at the store, or other food recommended by your doctor.

    If you sprinkle Zenpep on food, give the Zenpep and food mixture to your child right away.

    Give your child enough liquid to completely swallow the Zenpep contents or the Zenpep and food mixture.

    Look in your child's mouth to make sure that all of the medicine has been swallowed.

    Adults and Children

    Swallow Zenpep capsules whole and take them with enough liquid to swallow them right away.

    If you have trouble swallowing capsules, open the capsules and sprinkle the contents on a small amount of room temperature acidic food, such as applesauce, pureed bananas, or pears. Ask your doctor about other foods you can mix with Zenpep.

    If you sprinkle Zenpep on food, swallow it right after you mix it, and drink enough water or juice to make sure the medicine is swallowed completely.

  • What should I avoid while taking Zenpep?

    Do not crush or chew Zenpep capsules or its contents, and do not hold the capsule or capsule contents in your mouth.

    Do not store Zenpep that is mixed with food.

    Do not mix Zenpep capsule contents directly into formula or breast milk.

    Do not use Zenpep for a condition for which it was not prescribed.

    Do not give Zenpep to other people to take, even if they have the same symptoms you have. It may harm them.

  • What are possible food and drug interactions associated with Zenpep?

    No significant interactions have been reported with Zenpep at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Zenpep?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: bruising, constipation, cough, diarrhea, feeling full soon after eating, gas, headache, itching, nausea, rash, stomach pain, weight loss

  • Can I receive Zenpep if I am pregnant or breastfeeding?

    The effects of Zenpep during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Zenpep?

    If you miss a dose of Zenpep, wait until your next meal and take your usual number of capsules. Return to your regular dosing schedule and take your next dose at your usual time. Do not take two doses at once.

  • How should I store Zenpep?

    Store at room temperature. Avoid heat. Keep in a dry place in the original container.