What is Ziana?Ziana is an antibiotic and retinoid combination product used for the topical treatment of acne in patients ≥12 years old.
What is the most important information I should know about Ziana?Ziana may cause skin irritation such as dryness, redness, peeling, burning, or stinging. Stop Ziana and call your doctor if your skin becomes very red, swollen, blistered, or crusted.
If you use Ziana and experience severe diarrhea or gastrointestinal (stomach and intestine) discomfort, you should stop using this medication and contact your physician.
Do not use more than the recommended dose. A sunscreen should be applied every morning and reapplied over the course of the day as needed. You should avoid exposure to sunlight, sunlamps, UV light, and medicines that may increase sensitivity to sunlight. If you have sunburn, you should discontinue the medication right away and contact your physician. Ziana is not for vaginal use, or for use near the mouth or eyes.
Who should not take Ziana?Do not use Ziana if you have Crohn's disease, ulcerative colitis, or if you have developed colitis with past antibiotic use.
What should I tell my doctor before I take the first dose of Ziana?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ziana. Also, talk to your doctor about your complete medical history, especially if you are pregnant, plan to become pregnant, or if you are breastfeeding. Be sure your doctor knows about all the skin care products you use.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults and children ≥12 years: Apply a pea-sized amount to the face once a day at bedtime.
How should I take Ziana?Use Ziana exactly as prescribed, even though it may take some time for your acne to improve. Your doctor will tell you how long to use Ziana.
At bedtime: After washing your face gently with a mild soap and warm water, pat the skin dry. Apply a pea-size amount of Ziana to your fingertip and spread it over your face. Gently smooth it into your skin. Do not get Ziana in your eyes or mouth, on your lips, on the corners of your nose, or on open wounds. In the morning, apply a sunscreen and reapply during the day as needed.
Do not apply Ziana more than once a day and do not use too much of it because it may irritate your skin.
Do not wash your face more than two or three times a day. Washing your face too often or scrubbing it may make your acne worse.
What should I avoid while taking Ziana?Avoid excessive exposure to the sun, cold, and wind. Weather extremes can dry and burn the skin. Always use a sunscreen on Ziana-treated skin, even on cloudy days. Wear a hat and other protective clothing when you are in the sun.
Do not use sunlamps and tanning booths, medicated or rough soaps and cleansers, soaps and cosmetics that have a strong drying effect, and skin products that contain alcohol, astringents, spices, or lime. These products may cause increased skin irritation if used with Ziana.
If your face becomes sunburned, stop Ziana until your skin has healed.
What are possible food and drug interactions associated with Ziana?If Ziana is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Ziana with erythromycin-containing products.
What are the possible side effects of Ziana?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: change in skin color, diarrhea, skin dryness, redness, peeling, burning, stinging
Talk to your doctor about any side effect that bothers you or that does not go away. These are not all the side effects with Ziana. Ask your doctor or pharmacist for more information.
Can I receive Ziana if I am pregnant or breastfeeding?The effects of Ziana during pregnancy are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Ziana?Skip the dose you missed and resume treatment the following night.
How should I store Ziana?Store at room temperature away from heat and light. Keep the tube tightly closed.