Generic Name: Doxepin

  • What is Zonalon?

    Zonalon is a topical cream (applied directly on the skin) that is used for the short-term management of moderate itching in people with eczema or skin disorders that lead to chronic itching and scratching.

  • What is the most important information I should know about Zonalon?

    Zonalon is for external use only. Do not use it in your eyes.

    Do not use Zonalon for more than 8 days. Tell your doctor if you see no improvement after the recommended treatment time.

    Zonalon can cause drowsiness, especially if you apply it on greater than 10% of your body surface. Do not drive or operate hazardous machinery until you know how Zonalon affects you. Also, alcohol, antihistamines (such as diphenhydramine), and central nervous system (CNS) depressants can worsen this side effect while you are using Zonalon. Tell your doctor immediately if you experience excessive drowsiness.

  • Who should not take Zonalon?

    Do not use Zonalon if you have untreated glaucoma (high pressure in the eye) or urinary retention (inability to urinate normally).

    Do not use Zonalon if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Zonalon?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zonalon. Also, talk to your doctor about your complete medical history, especially if you have glaucoma or urinary retention.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Apply a thin film of the cream to the affected and surrounding skin area(s) 4 times a day, with at least 3-4 hour intervals between each application.

  • How should I take Zonalon?

    Apply Zonalon exactly as prescribed by your doctor. Do not use Zonalon for longer than 8 days. Prolonged use may lead to unwanted side effects.

  • What should I avoid while taking Zonalon?

    Do not drive or operate hazardous machinery until you know how Zonalon affects you.

    Do not drink alcohol while using Zonalon.

    Do not use occlusive dressings over the area where you have applied Zonalon.

  • What are possible food and drug interactions associated with Zonalon?

    If Zonalon is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zonalon with the following: alcohol, certain antidepressants (such as amitriptyline or imipramine), cimetidine, monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine), or tolazamide.

  • What are the possible side effects of Zonalon?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: application-site reactions (such as burning and stinging), changes in taste, dizziness, drowsiness, dry mouth, emotional or mental changes, swelling, tiredness

  • Can I receive Zonalon if I am pregnant or breastfeeding?

    The effects of Zonalon during pregnancy and breastfeeding are unknown. Zonalon can be found in your breast milk if applied during breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Zonalon?

    If you miss a dose of Zonalon, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store Zonalon?

    Store at room temperature.