Generic Name: Zonisamide

  • What is Zonegran?

    Zonegran is taken with other medications to treat partial seizures in adults.
  • What is the most important information I should know about Zonegran?

    Zonegran can cause serious reactions in some patients. Call your doctor right away if you experience any of the following: rash, fever, sore throat, sores in your mouth, bruising easily, sudden back pain, abdominal pain, pain when urinating, bloody or dark urine, decreased sweating or increased body temperature (especially if you are under 17 years old), depression, thoughts that are unusual for you, or speech or language problems. Zonegran may cause drowsiness or coordination problems. You should take it with caution if you have any type of kidney or liver problems.
  • Who should not take Zonegran?

    Do not take Zonegran if you are allergic or sensitive to it or any of its ingredients. Also, you should not take Zonegran if you are allergic to sulfa-derived medications such as sulfamethoxazole/trimethoprim.
  • What should I tell my doctor before I take the first dose of Zonegran?

    Mention all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Zonegran. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems, if you are pregnant, plan to become pregnant, or if you are breastfeeding.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults (16 and older): The usual starting dose is 100 milligrams (mg) taken once a day for 2 weeks. The dose is usually increased to 200 mg per day for at least 2 additional weeks, after which the total daily dose may be increased to 300-600 mg per day depending on your condition.

  • How should I take Zonegran?

    Zonegran should be taken exactly as prescribed. It is important to swallow the capsules whole; do not break or crush them. You should drink at least 6-8 glasses of water daily while taking Zonegran, which will help to prevent kidney stones. Do not suddenly stop taking it unless you are instructed by your doctor.
  • What should I avoid while taking Zonegran?

    You should not drive a car or operate heavy machinery until you know how Zonegran will affect you.
  • What are possible food and drug interactions associated with Zonegran?

    If Zonegran is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zonegran with carbamazepine, phenobarbital, or phenytoin.
  • What are the possible side effects of Zonegran?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: agitation, dizziness, drowsiness, headache, loss of appetite, nausea

  • Can I receive Zonegran if I am pregnant or breastfeeding?

    The effects of Zonegran during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
  • What should I do if I miss a dose of Zonegran?

    Talk to your doctor about what to do if you miss a dose. Depending on your condition, your doctor will decide when your next scheduled dose should be.
  • How should I store Zonegran?

    Store at room temperature, in a dry place and protected from light.