Generic Name: Somatropin

  • What is Zorbtive?

    Zorbtive is a medicine that contains human growth hormone. It is used to treat Short Bowel syndrome in people who are on a special diet. Zorbtive can help your bowel take in more water, electrolytes (chemicals that are important for the cells in your body to function, such as sodium and potassium), nutrients, or lower your need for feedings given intravenously (through a vein in your arm). Zorbtive is administered subcutaneously (just below the skin).

  • What is the most important information I should know about Zorbtive?

    Zorbtive can cause allergic reactions including trouble breathing, skin redness, and warmth all over the body. Stop using Zorbtive and get emergency medical help immediately if you get any of these symptoms.

    Zorbtive can cause swelling, particularly in your hands and feet, pain, or stiffness. Carpal tunnel syndrome (a nerve disorder that causes numbness and tingling in your wrist and hand) can also occur during treatment with Zorbtive.

    Zorbtive can increase your blood sugar levels, or cause new or worsen diabetes. Check your blood sugar levels regularly. Your doctor may need to adjust the dose of your diabetes medications.

    Zorbtive can cause pancreatitis (inflammation of the pancreas). Tell your doctor if you experience severe pain in the upper stomach area, swollen and tender stomach, sweating, nausea, vomiting, fever, yellowing of your skin and whites of your eyes, or a fast heartbeat.

    Increased pressure in your brain can occur with the use of growth hormone products. This may include papilledema (swelling of the optic disk), visual changes, headache, nausea, and/or vomiting.

    Zorbtive can be reconstituted with Bacteriostatic Water for Injection, which contains benzyl alcohol as a preservative. Benzyl alcohol can harm newborn babies. You can use Sterile Water for Injection, but you can use only one dose per vial and discard the unused portion.

  • Who should not take Zorbtive?

    Do not use Zorbtive if you are allergic to it, any of its ingredients, or benzyl alcohol if you are mixing Zorbtive with Bacteriostatic Water for Injection. Also, do not use Zorbtive if you have an active cancer or if you have a serious medical condition after having an open heart or abdominal surgery, serious injuries involving many body systems, or breathing problems (such as sudden respiratory failure).

  • What should I tell my doctor before I take the first dose of Zorbtive?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zorbtive. Also, talk to your doctor about your complete medical history, especially if you have cancer, respiratory problems, pancreatitis, diabetes, increased pressure in your brain, kidney or liver problems, carpal tunnel syndrome (a nerve disorder that causes numbness, tingling, or burning sensations in the thumb and fingers), trauma, heart or abdominal surgery.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you based on your weight.

  • How should I take Zorbtive?

    Use Zorbtive exactly as prescribed by your doctor. Follow the special diet that your doctor prescribes for you to be on while using Zorbtive. Your doctor will tell you the amount of food to eat and the times of the day that you should eat. Do not change your dose or your diet unless you talk with your doctor.

    Allow the medicine to warm to room temperature before injection. Change the sites of injection every day to avoid injection-site reactions.

    Always use a new, unopened needle and syringe for each injection.

    Your doctor will show you and/or your caregiver how to inject this medicine, as well as how to properly dispose syringes and needles. Please review the instructions that came with your prescription on how to properly use Zorbtive.

  • What should I avoid while taking Zorbtive?

    Do not inject Zorbtive solution if it is cloudy immediately after reconstitution or refrigeration.

    Do not reuse needles and syringes.

    Do not inject Zorbtive into an area of your skin that is sore, red, infected, or damaged.

    Do not drink water, soda, fruit juices, or alcohol while using Zorbtive. Your doctor will tell you which liquids are okay to drink.

  • What are possible food and drug interactions associated with Zorbtive?

    If Zorbtive is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with Zorbtive: diabetes medications or glucocorticoids (such as prednisone).

  • What are the possible side effects of Zorbtive?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: dizziness, gas, headache, injection-site reactions (such as bruising, itching, pain, rash, redness, skin bumps, soreness, or swelling), joint or muscle pain, nausea, stiffness, stomach pain, vision problems, vomiting

    If you experience symptoms of tingling feeling in your hands or wrists; increased thirst; increased urination or dizziness; swelling of your head, face, heads or feet; unusual headaches; problems with your eyesight; nausea or vomiting, contact your doctor immediately.

  • Can I receive Zorbtive if I am pregnant or breastfeeding?

    The effects of Zorbtive during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Zorbtive?

    If you miss a dose of Zorbtive, inject it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not inject two doses at once or more than one dose each day. If you miss more than 3 consecutive doses, call your doctor for further instructions.

  • How should I store Zorbtive?

    Store at room temperature. After mixing, store in the refrigerator for up to 14 days. Do not freeze.