Zyclara

Generic Name: Imiquimod

  • What is Zyclara?

    Zyclara is a topical cream (applied directly on the skin) that is used to treat actinic keratosis on your face or balding scalp. Zyclara is also used to treat warts on or around your genitals or anus. New warts can develop during therapy, as Zyclara is not a cure.

  • What is the most important information I should know about Zyclara?

    Zyclara is for external use only. Do not use it in or on your mouth, eyes, lips, nose, or inside your anus or vagina. If you get the cream in your mouth or eyes, rinse the area well with water immediately.

    Zyclara can cause local inflammatory reactions, including redness, swelling, erosions, ulcerations, drainage, flaking, scaling, dryness, scabbing, crusting, or skin color changes. Zyclara can also cause "flu-like" symptoms, including tiredness, fever, nausea, muscle pain, or stiffness. Tell your doctor immediately if you are bothered by any of these symptoms.

    Do not expose your treated skin area(s) to the sun. If you cannot avoid this, use sunscreen or wear protective clothing if you go outside during daylight while you are using Zyclara. If you have a sunburn, wait until it fully recovers before you start this medicine.

  • Who should not take Zyclara?

    Do not use Zyclara if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Zyclara?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zyclara. Also, talk to your doctor about your complete medical history, especially if you have immune system problems, sunburn, or other skin problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Actinic Keratosis

    Adults: Apply a thin layer to the affected area(s) once a day, for 2 weeks, then stop using for 2 weeks, and then apply once a day again for 2 weeks.

    Genital or Anal Warts

    Adults and adolescents ≥12 years: Apply a thin layer to the affected area(s) once a day, for up to 8 weeks.

  • How should I take Zyclara?

    Apply Zyclara exactly as prescribed by your doctor. Apply Zyclara just before your bedtime. Wash the affected area(s) with mild soap and water, and allow the area to dry. Wash your hands, and rub a thin layer of the cream into your skin. Wash your hands after application. Leave the cream on the treated area for the amount of time prescribed by your doctor, and do not bathe or get the area wet. Wash the treated area with mild soap and water about 8 hours after the application.

    Zyclara is available in packets or a pump. Prime (to release into the air the dose that is already in the device) the pump before using it for the first time only. Please review the instructions that came with your prescription on how to properly use your Zyclara packets or pump.

  • What should I avoid while taking Zyclara?

    Do not use Zyclara in or on your mouth, eyes, lips, nose, or inside your anus or vagina.

    Do not cover the treated area with bandages or other closed dressings. However, cotton gauze dressings or cotton underwear can be used after applying Zyclara.

    Do not excessively expose your skin to the sun, sunlamps, or tanning beds.

    Do not have sexual contact including genital, anal, or oral sex when Zyclara is on your genitals or the skin around your anus. Zyclara can weaken condoms and vaginal diaphragms.

  • What are possible food and drug interactions associated with Zyclara?

    No significant interactions have been reported with Zyclara at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Zyclara?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: dry skin, "flu-like" symptoms, headache, itching, nausea, pain, skin breakdown, skin crusting or scabbing, skin flaking or scaling, skin irritation, skin redness, swelling, tiredness, vaginal swelling

  • Can I receive Zyclara if I am pregnant or breastfeeding?

    The effects of Zyclara during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Zyclara?

    If you miss a dose of Zyclara, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store Zyclara?

    Store at room temperature. Do not freeze. Store Zyclara pumps upright.