Generic Name: Hydrocodone

  • What is Zydone?

    Zydone is a pain medicine that contains the narcotic painkiller hydrocodone and the non-narcotic painkiller acetaminophen. Zydone is used for the relief of moderate to moderately severe pain.

    Zydone is a federally controlled substance because it has abuse potential.

  • What is the most important information I should know about Zydone?

    Zydone has abuse potential. Mental and physical dependence can occur with the use of Zydone when it is used improperly.

    Zydone can cause serious breathing problems that can become life-threatening, especially when it is used in the wrong way. Tell your doctor if you have any lung or breathing problems; your doctor will monitor you.

    Zydone contains acetaminophen, which can cause severe liver injury. Do not take more than 4,000 milligrams (mg) of acetaminophen per day or take other products containing acetaminophen. The risk of liver injury can be higher if you have underlying liver disease or drink alcohol while taking Zydone.

    Zydone can cause allergic reactions or anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Stop taking Zydone and tell your doctor immediately if you develop a rash, difficulty breathing, or swelling of your face, mouth, or throat.

    Zydone can impair your mental or physical abilities. Do not drive or operate machinery until you know how Zydone affects you. Speak to your doctor about when you can start performing these activities.

  • Who should not take Zydone?

    Do not take Zydone if you are allergic to it, any of its ingredients, or other narcotic painkillers.

  • What should I tell my doctor before I take the first dose of Zydone?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zydone. Also, talk to your doctor about your complete medical history, especially if you have lung or breathing problems; brain problems or head injury; abdominal problems; severe liver or kidney problems; hypothyroidism (an underactive thyroid gland); adrenal gland problems; urinary blockage; alcoholism; history of or a present drug abuse or addiction problem; or a family history of drug abuse or addiction problem.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you based on your condition, and severity of your pain.

  • How should I take Zydone?

    Take Zydone exactly as prescribed by your doctor. Do not adjust your dose without speaking to your doctor.

  • What should I avoid while taking Zydone?

    Do not drive or operate machinery until you know how Zydone affects you.

    Do not drink alcohol while you are taking Zydone. Alcohol can increase your chance of having dangerous side effects.

  • What are possible food and drug interactions associated with Zydone?

    If Zydone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zydone with the following: alcohol, antihistamines (such as cimetidine or diphenhydramine), certain antidepressants (such amitriptyline); certain antipsychotics (such as clozapine, haloperidol, or olanzapine), monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine), or other medications that slow down your brain function (such as alprazolam, diazepam, or phenobarbital).

  • What are the possible side effects of Zydone?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, difficulty breathing, dizziness, drowsiness, hearing impairment, itchiness, lightheadedness, nausea, rash, urinary retention (inability to urinate normally), vomiting

  • Can I receive Zydone if I am pregnant or breastfeeding?

    The effects of Zydone during pregnancy are unknown. Zydone can be found in your breast milk if you take it during breastfeeding. Do not take Zydone while you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Zydone?

    Zydone should be given only as needed.

  • How should I store Zydone?

    Store at room temperature. Protect from light.